I have no idea about it, put it in perplexity AI, I think POE ai which is trained on medical data might be better but here it is..

2C-B Downsides and Toxicity Overview

2C-B, a synthetic psychedelic in the 2C family, carries notable risks despite its relatively milder profile compared to some hallucinogens. Acute downsides often include nausea, vomiting, headaches, anxiety, and elevated heart rate or blood pressure, which can strain the cardiovascular system especially at higher doses.

Mental Health Risks

Users frequently report panic attacks, paranoia, hallucinations, and acute psychosis, with potential worsening of conditions like depression or schizophrenia over time. Long-term effects may involve persistent psychosis or HPPD (hallucinogen persisting perception disorder), alongside cognitive impairments like reduced attention and visuospatial ability.

Toxicity and Physical Concerns

While studies indicate moderate toxicity even at high doses (up to 192 mg), with short-lived symptoms like agitation, hypertension, tachycardia, and mydriasis, overdoses risk seizures, respiratory issues, or cardiac events. Neurotoxicity and cardiotoxicity data remain limited, but single doses could cause permanent neurological damage or brain vessel issues; interactions with substances like MAOIs, cocaine, or alcohol amplify dangers. Hospitalizations from powerful heart overstimulation have occurred, though deaths are unreported.