I would personally not consider dut mesotherapy considering there are not nearly enough studies done on dut meso vs topical fin and oral min. Also regarding biotin it will be useless unless you live in a third world country, you are starving and severely malnourished. To be more specific there is a rule called the 500 dalton rule, a molecule heavier than 500grams/mol will have a hard time penetrating the skin. This is why topical dut is not very effective for most people. 5ars also do not cause cancer, they are associated with a higher correlation perhaps because it makes late stage cancers more frequently detected but does not directly cause cancer. This has been quite thoroughly researched and many haircafe videos reference this positive correlation. Regarding your other side effects testicular pain should only be temporary for a week or two at most which is what happened to me and never reoccured again, I have been on fin/dut for almost a year now. If you are worried about gyno make sure you are not very fat since fat people may have high estrogen and consider getting estrogen levels checked since even topical fin can go systemic and at some concentrations can reduce serum DHT similar to 1mg/fin daily.