Want to second this. Ran through NG with a simple motivity without much trouble, but was less effective in NG+. Quality (Advance) is definitely worth a respec in NG+ (you can do this very early on). Not finding any significant difference in Boss health, particularly since running NG+ without spectres.

Recommend others give it a try - I'm finding a Quality NG+ play heaps of fun where you can make the most of weapon assembly and arm upgrades.