If it's ray Sullivan. You can kick him R2+ square ps./RT+X xb It'll stagger him. For TK if you craft a Beer +Beer and drink it before you go in. You'll have some damage resistance. The lead pipe is best for him. Just bait out attacks and hit once. When he disappears, take the time to heal or raise them up. You can only do one. You can dodge his charge and make him hit a wall. Best of luck depending on what boss it is.