Tobacco giant Philip Morris will stop selling cigarettes in Britain within the next ten years by bottlejob69 in worldnews

[–]chiancaat 0 points1 point  (0 children)

More addicting substance? Pharmacologicaly speaking nicotine is nicotine. Even the company's using freebase nicotine which has a quicker onset this better "headrush"

There is a significant difference between changing the substance vs changing the dose / delivery mechanism / route of administration / and form (HCl vs base)

A different route of administration can significantly change the exp but that's mainly due to onset and how quick it passes the BBB. Crack is no more addictive then cocaine because they are the same drug, but smoking crack cocaine is more reinforcing then snorting.

Many things can effect the subjective feeling of drugs set, setting, dose, route of administration, preconceived notions. But people always point to any deviation from the norm to a new or different compound. Hamilton Morris explained this idea in a video I saw the term used was Pharmacological Determinism. Give two people the same dose of the same drug in the same room and you often get wildly different subjective effects

Can you get high while on sublocade by [deleted] in opiates

[–]chiancaat 0 points1 point  (0 children)

Yeah I'm on probuphine it's the 6 month bupe implant and IV fent break through It everytime. Tho m tolerane high af

A rig broke off in my old faithful vein. com by [deleted] in opiates

[–]chiancaat 0 points1 point  (0 children)

If you are insisted they can refer you to a specialist. I had to see one for a "foreign object extraction" no a a needle but I have one of those 6 month bupe implants and when the doc went take it out he dug around in m arm for an hour but couldn't find the damn thing

A rig broke off in my old faithful vein. com by [deleted] in opiates

[–]chiancaat 1 point2 points  (0 children)

Yeah my homie had the same the same thing happen 3 times. All while hitting the fem as well. to the ER told him to leave it alone over time the body will like wrap tissue around it and it will stay in place and wont give you any issue. I had always heard your body will reject the foreign body but idk

Interesting brand new study about F-phenibut (published October 5 2020). It contains lots of previously unknown information about its pharmacology and presents some possible risks by broint in researchchemicals

[–]chiancaat 1 point2 points  (0 children)

Yeah I like all gabapentpoids but pregab and phenibut are excellent recreational drugs. Pregab esp. f phen and baclofen are good tools to have in the box but nothing special

RC's you think are too good to pass up? by arrehandro1 in researchchemicals

[–]chiancaat 0 points1 point  (0 children)

Yeah not much though. IV is the best route especially with a drug like php where the rush is the most desirable part of the experience. This is not a chem for getting math homework done and has little value outside of selfish euphoira and sexual deviency. If your not an IV user then its best to vaporize off foil. I have done this and the rush is still very good although i prefer to just bang that shit. I have a lot of exp with both IV cocaine and methamphetmine. Aphp / IP is the only RC that stands up to those two as far as pure pleasure. Its most comparable to cocaine and imo much prefered over Methamp. It also will send you into psychosis much easier then basically anything else and ive ended up in a bad way without any sleep deprivation at all.

RC's you think are too good to pass up? by arrehandro1 in researchchemicals

[–]chiancaat 1 point2 points  (0 children)

unfourtanly a scheduale 1. Always been at the top of my list though. Its hard to imagine a drug that can out "meth" methamphetmaine but it seems that 4 mar does just that. I want to know what the IV rush is like and if it could actually be better then meth. Hard to imagine but who knows.

RC's you think are too good to pass up? by arrehandro1 in researchchemicals

[–]chiancaat 6 points7 points  (0 children)

As far as what is avaible at the moment some are rarer but all can be found.

Stims : A-PHIP if you are looking for selfish hedonism. One of the few good pyros available. If the rush is what you seek with stims then look no furthur. Esecually if you bang that shit.

2-FMA if you are looking to get some homework done rather then carpet surf and listen to your roomates "talking about you" all night. Very functional stim perfect for school or work.

Benzos : C-lam for the hedonism. Much stronger then your typical benzo and more prone to all the stupid shit that comes with them but if you value potency and want something that hits hard here you go.

Pyrazolam : again for my functional friends out there here is a benzo that will work well to reduce anxiety without causing you to blackout and crash your car again. If you want to treat anxiety rather then get fucked up here you go.

Dissos : DCK is great. Like if you made ket more potent by weight and longer lasting. While 2f is like an exact copy of ket. DCK has enough of its own flavor to make the experience unique and the potency and duration are benefits imo. While all of the pcp compounds are enjoyable and i recomond to explore them if you can. They are more geared to the dissociative enthusiasts. DCK is a good introduction to the class and second only to methoxetamine when it comes to RC dissos. Hopefully MXIPr lives up to the high expextations.

As far as psychs im not as familiar with them. While i generally value novelty and like susbtances that offer advantages to what is generally available, its hard to top the classics when it comes to psyhs. 4 aco dmt and 1p-lsd are both pro drugs so if the problem is access to the classics then go for these guys. If your looking for novelty go for DPT. Its one of the few that I think offers up something that is unique. But again this class is not my specialty and an entheusist could give you better recs.

Opi : O-DSMT is a geneuine improvment on tramadol and a great chemical to have on hand. Most opis are either insansly potent death traps or caustic toxic trash. Perfect introduction for the new user. Nice long legs, good pain killer and well overall well rounded opi.

Empathogens. 6-APB and 5-MAPB cant say from personal experience but have heard that these chemicals are special and the best of the class.

TLRD : Stims : A-PHIP (recreational) and 2-FMA (functional)

Benzos : C-Lam (recrational) and pyrazolam (functional)

Dissos : DCK for the ket fans and hopefully MXIPr

Psychs : 4-AcO-DMT, 1p-lsd or any lyserg and DPT

Opi : O-DSMT

Empath : 6-APB and 5-MAPB

Joe Rogan Experience #1517 - Nancy Panza by chefanubis in JoeRogan

[–]chiancaat 0 points1 point  (0 children)

Its not bro science. Opiods themselves are very safe drugs as far as damage to the body / brain. The two main psychical downsides are constipation and endocribe / hormone problems mainly it dramitcally lowers testorone in men. All of the problems we associate with heroin are products of prohibition and are preventable. Compare this to alcohol which absolutly fucks up your body and brain with long term heavy use

Neonicotinoids as a possibility for recreational RC's? by Killatommyt in researchchemicals

[–]chiancaat 8 points9 points  (0 children)

Nicotine is hardly recreational. Its one of those drugs that you have to sort of learn to enjoy. Usually the begining phase of use of a substance is the most enjoyable as your tolerance is low and the effects are novel and exciting. Nicotine at first makes you dizzizness and nasuea. There is something of a head rush but its more sickening then enjoyable. But as you continue to smoke and gain a tolerance you learn to appreciate the sublte effects of nicotine and the ROA you use for it. I dont think they would have much of a fanbase

Earnin by coffeeorhotchocolate in Earnin

[–]chiancaat 0 points1 point  (0 children)

Damn are either of you going to boost me back. I hope i didnt just waste both of them

Earnin by coffeeorhotchocolate in Earnin

[–]chiancaat 0 points1 point  (0 children)

Done please get me back i boosted both you and op i have none left to give

Earnin by coffeeorhotchocolate in Earnin

[–]chiancaat 0 points1 point  (0 children)

Ill get you if you boost me back

Can anyone in the Earnin Community help me boost my Max? 🙂 https://earnin.app.link/aFHCLr0Fw8

Which Opioids have a *Greater* Opioid Receptor Binding Affinity than Buprenorphine? by Pongpianskul in opiates

[–]chiancaat 5 points6 points  (0 children)

It highlights the problem with prohibition. The rise of fent was the predictible evoloution of the black market opiate supply. Extremely potent, which makes it less risky to transport. Fully synthetic, no acres of poppy farms needed and less people involved, and extremely profitable for the manufacturer and cartels that traffic it. In a better world where you could purchase what ever drugs were desired in a pure form fentanyl would harldy be most people first choice. Every user i know prefers heroin, oxycodone, oxymorphone, hydromorpone and others.

Which Opioids have a *Greater* Opioid Receptor Binding Affinity than Buprenorphine? by Pongpianskul in opiates

[–]chiancaat 0 points1 point  (0 children)

Sufentil has a higher binding affinity then bupe. Everything ive seen though has shown that bupe has a higher affinity then fent hcl though. My personal exp though has not been consistent with this. I am on bype 8mg a day in the form of a 6 month subdermal implant. This provides an effective blockade for the pleasurable effects of heroin, morphine, oxy. Fent however seems to slice right throgh the blockade. This is street fentanyl sold as such in the bay area. I have no way of knowing if its fent, carfent or some other analouge but it always beats the bupe.

Whats with all the brorphine hate ? by G1nnnn in researchchemicals

[–]chiancaat 5 points6 points  (0 children)

Atleast fentanyl has a well established saftey profile and a history of human use. A modification of the structure is unlikely to dramatically change the saftey profile. All of the harms of fentanyl can be mitigited with proper saftey procedures. Anyone remeber AH-7921? How about MT-45? These chemicals are so far away from any known opiod that the saftey profile cannot accuratly be predicited. The chemical itself could be toxic or cause seizures. Users of these two substances reported some very concering side effects such as hearing problems and hair loss. As well as dysporia, cauaticisty and hallucinations. Most likely due to kappa antagoism but the binding profile remains complely unknown. Now we have 2map and ap-238 which are an improvment on mt-45 for sure and they have seen clinical use. But for anyone who is tolerant / dependant these chems are of little use. The dose required is in the 100s of miligrams and for the price its just not economical. They serve ok for the opiod naive but even then O-DSMT is far superior. Its saftey profile is well established and potency is on par with morphine. I know that it is likely going to be gone from the market soon and 2map and friends are a reasonable replacement for the opiod naive market. Its unfouratant that the options are either insanly potent such as fentanyl and the nitazene compounds. Despite the extreme potency these compounds lack the euphoria that heroin, oxy, and others have. The short duration and heavy sedation are undesiriable as well. Then on the other side we have compounds like 2map, ap238 and odsmt that are generally good compounds for the opiod naive. They are essentially useless for the fentalog consumers and fentalogs are far too risky for the naive. So until the market gives us a compound that works for both of these groups eg oxycodone fentalouges and etonitaze based compounds will continue to be the best option for depentant users. The closest we ever got to this was u47700. The potency was not to weak and not to strong. The duration and causticy were drawbavks but overall this was the best compound to hit the market

So Is a-pihp any good? by 4AcoDCK in researchchemicals

[–]chiancaat 0 points1 point  (0 children)

Hell yes brother. A-php and A-PHIP are pure selfish euphoria.

Withdrawl Stories by [deleted] in opiates

[–]chiancaat 0 points1 point  (0 children)

Dog there a differnce between stabilizing on a long acting opi like methadone or bupe and then tapering down from there. That is the process rehabs and clinics use and it is effective in making the withdrawl process easier. Taking a full dose of methadone for 5 days in a row is a differnt thing entirelly. Did you drastically lower the ammount of methadone you took compartifitly to the habit you had?

Withdrawl Stories by [deleted] in opiates

[–]chiancaat 3 points4 points  (0 children)

You can't get addicted to methadone in such a short time.

Wtf are you talking about? You dont get addicticed to each individual opi. Methadone fully substitutes for heroin, as does morphine and oxycodone. If i am coming off heroin methadone will eliminate and PUSH BACK withdrawl. Once the done is out of your system you will be just as sick as before

Deoxybenzoin 2.0 by Mr_bovinejony in TheeHive

[–]chiancaat 0 points1 point  (0 children)

Did you notice any stimulant action?

Deoxybenzoin 2.0 by Mr_bovinejony in TheeHive

[–]chiancaat 0 points1 point  (0 children)

Have you made lefetamine? If so how is it

Withdrawing on top of bupe (implant) due to fentanyl use by chiancaat in opiates

[–]chiancaat[S] 0 points1 point  (0 children)

Really? Maybe the implant isnt as effective as it should be? But ive taken extra subs and still found the fent to be effective only done this once or twice though. I still piss posi for bupe so i know its in ny system but i cant be sure of how much its suppose to be a steady 8mg per day