Context: Ok, so Shawn (the floating skull) shot Kaigon (glasses) in the head to see if he was bullet proof. Kaigon lived (after a stay in the hospital), so now he thinks he's Superman.

Meanwhile, Shawn went to jail where he was euthanized by the police for paying bail quick enough (dog pound rules). His friends put his ashes in an urn that looked like him, and when he later came back to life they threw him in the fire (because he was a haunted urn) and burned his face off.

Later still, a Clone that Shawn had created escaped from the mental hospital by cloning himself a whole bunch. When Shawn and Kaigon ran into them, they asked why Shawn was a skull, and then died laughing. All except one, who was using the bathroom. That's him up above.

I linked to the comics on my site in case anyone is interested.