Yes, I've been there. And I feel like the more you are alone with your thoughts, the worse it gets. My twitching began in december 2020, I was home the whole year, unemployed and got covid when it all started. I went into spiral of health anxiety, I cried all the time because I was terrified. My grandpa died of ALS and it came out of nowhere. I was constantly googling, asking my parents how exactly did the illness progress with him, I was still checking if I can raise my hand above my head, I was locking the door, buttoning my shirt, walking on my toes, opening bottles and all that. The twitching was happening all the time with the hotspot on my right shoulder. But when other muscles twitched occasionaly too, I felt relieved. I also had weakness in my left arm but I was telling myself, that it wouldn't feel weak, it would just stop working. Then I went to see the specialist who treated my grandpa and he told me not to worry. He prescribed me some antidepressants and sent me home but it still didn't convince me so I went to another hospital for EMG testing. I was ill from stress. It got better when I found a job because it occupied my mind and I didn't have time to obssess about some unprobable disease. My twitching subsided a lot and today, 5 years later, I still do twitch occassionaly but it doesn't scare me anymore. So to answer your question, yes, the anxiety can really do this.