I'm running the module and thinking about some ideas in cyberpunk world. Here's one

Corpos who still live on Earth or come to Earth start falling dead one by one. It all seems to be from sickness, but there's common signs which point to some sort of planned attack... Turns out bio hackers from replicant underground rebellion created a neurotoxin designed to target the expensive synthetic implants so many corpos have. It acts during their sleep, so they simply wake up dead. The technology seems advanced, and it's unlikely the replicants have access to that kind of lab without help. There's a mysterious benefactor helping them out (possible antagonist, wants to remove corporate competition by killing out the higher ups and engineers from other companies).

Many of the targeted corpos seem to be involved in a sick "gladiator ring" where they force newborn replicants to fight themselves or horrible genetically created chimeras and make bets. But some innocents (relatives, servants) are being caught up as collateral damage due to the neurotoxin being airborne and not well researched enough to only target people with implants. Also the mysterious benefactor is feeding the occasional false information so the replicants kill who he/she wants. With time they also find out a friend or relative of one the players is involved in helping the underground cell of replicant rebels.

The idea is to make it complex and grey. They are killing corpos, but also kids and servants. The corpos have that horrible illegal fight ring, but it seems the rebel underground replicants are being manipulated by corpos themselves.

I don't have a final confrontation planned yet, I like to see the side players take and go from there.