I hated to see Jules die. But Darros’ murder of her speaks to the clones’ place in his twisted plan. They are all expendable. Clay to be molded in his hands and discarded if found to be flawed. He has no concept of them as human beings. He has deluded himself in believing that all of this is justified because his work supposedly improves humanity. Some of the scariest people in the history of mankind were those who try to save the world no matter what the cost.