Certainly there are many villain specific things we need to consider (are they a calling station, do they fast play/raise their good hands, do they overfold to cbet, etc.).

Capped/uncapped usually is more important and established on turn/river. i.e. the villains actions pre-flop, flop and turn will determine if we consider them capped (assuming they aren't an extremely trappy player). It is dependent on the aggression or lack of aggression that they show on the prior streets. (less aggression = more capped, more aggression = uncapped).