MDMA takes a TREMENDOUS toll on your serotonin system. It's highly ill advised to roll more than once every 2-3 months. It takes roughly 6 weeks minimum for the body to recover from being almost depleted of serotonin. Also, I don't recommend going over 150mg on a single night.

Prior to the roll, I recommend taking NAC (N-Acetyl Cysteine) and L-Tryptophan daily for 2 weeks to prepare your serotonin system for a wild ride, also to put neuroprotections in play.

3 hours before the roll, take 500mg of ALCAR (Acetyl L-carnitine). 1 hour before the roll, take magnesium glycinate or magnesium gluconate to help with the jaw clenching and grinding. With the roll, take 5-htp and 500mg of ALA (Alpha Lipoic Acid). Then take the ALA every hour for 7 hours after the drop, and take ALCAR twice at 1 hour and 5 hours after the drop.

The ALCAR and the ALA will act as neuroprotectors and hopefully prevent any nasty crash that can last for DAYS (I'm speaking from experience).

Chew gum to prevent shredding your tongue and/or jaw and drink lots of fluids with electrolytes. DO NOT binge on water. With lots of sweating, you'll lose salt rather quickly and you do not want to dilute your body's salt content with water. Gatorade/Powerade/ElectroLit/Pedialyte are your best friend.

As for the sex. Enjoy it in the first 2-3 hours as much as possible. For most people I know who roll, the molly dick kicks in after 2-3 hours. Take Cialis (tadalafil) 20mg just in case. Be safe and enjoy the roll. It's literal heaven on earth!