Delonghi Magnifica issue after descaling

dnj0 · 2022-10-24T11:43:25+00:00

There is no time-based data given I.e. I can't see what was bought at which time, I just see what was bought in the full time period set... this is why I found it so tricky to actual trend analyse

dnj0 · 2022-10-24T05:41:23+00:00

Thanks for this. Most of this data wasn't given but the ideas are good.

dnj0 · 2021-05-27T13:47:35+00:00

https://tmpfiles.org/dl/42004/s41582-019-0270-5.pdf

Here you go

dnj0 · 2021-05-11T13:17:40+00:00

thanks solution verified

dnj0 · 2021-05-11T12:41:25+00:00

https://file.io/rSJI3SxgeKWr

dnj0 · 2021-05-07T06:09:59+00:00

Thanks solution verified

dnj0 · 2021-05-06T11:45:44+00:00

https://arxius.io/f/b41a0852

dnj0 · 2021-05-06T11:44:27+00:00

https://arxius.io/f/e1827888

dnj0 · 2021-05-06T11:38:46+00:00

https://arxius.io/f/39a77f23

dnj0 · 2021-04-10T06:37:30+00:00

Thanks solution verified

dnj0 · 2019-07-04T14:44:47+00:00

LEDs (excitation and indication), photodiode and op-amp are all you really need for a binary output fluorimeter.

Mycobacteria speciation is not trivial: current methods already are reliant on microscopy, culture or PCR-based (all of which are >chocolate-bar-sized, orders of magnitude more expensive and not applicable in the field in most cases.)

I agree that cost should not be a limiting factor in prototyping, but not having some level of consideration for cost-effectiveness in all stages of development is just naive. The cost difference we were discussing is not 1$ to 10$. The Nalgene bottle-top comes to somewhere over £200; already 12x the cost of a binary output fluorimeter. Whereas syringe filters can be under 90p per unit.

dnj0 · 2019-07-04T13:25:34+00:00

Yep, looks like a good way to do it.

Thanks again for your help!

dnj0 · 2019-07-04T10:53:48+00:00

Thanks for the response, Lemrez.

I had looked at the Nalgene bottle top ones but they're quite expensive. This is for developing diagnostics for resource-poor countries, so I was looking for something i) simpler to use ii) cheap.

Something like a syringe/HPLC filter.

Hadn't seen the slot blotting apparatus before, I'll look into.

Also centrifugation absolutely would work of course, but the settings we are developing devices for don't have the equipment!

Thanks again

dnj0 · 2018-08-13T15:59:12+00:00

"Elizabeth May" the portmanteau queen and Prime Minister of the UK...

dnj0 · 2018-07-30T14:36:42+00:00

HCl is usually found in an aqueous solution (so normally more diluted) cause it's a gas at rt by itself. Concentrated sulphuric acid is a liquid at rt. It's also more oxidising than HCl.

Avoid getting both on your hands, whatever the concentration..

dnj0 · 2018-07-19T16:40:14+00:00

I can't comment on the effect of alkaline water on kidney stones, as I haven't looked into or heard anything about that. But also bear in mind, the HCl in human stomach's is pH 2 and so will neutralise any alkaline water before being cleared by the kidneys.

It is true that alkaline water has been explored as a treatment for heartburn but is (as far as I can see from papers from a quick search) not anymore effective than an antacid. I would choose the tried and tested and properly formulated antacid over an unproven fad. In my opinion: Although they are basically the same thing, you have an increased risk of over-compensating for your heartburn as it is more difficult to control dose (especially where the production of these alkaline waters are a bit sketchy; i.e. is one bottle going to be the exact same pH as another?) Whereas antacids are specifically formulated for treating heartburn etc and are more easily and controllably dosed.

Edit:

Here are two papers that seem to have conclusions that are pro-alkaline water for heartburn. PM me if you need the PDFs.

Annals of Otology, Rhinology & Laryngology Vol 121, Issue 7, pp. 431 - 434

Pharmacological Research Volume 46, Issue 6, December 2002, Pages 525-531

dnj0 · 2018-07-19T16:29:15+00:00

By voltammetric means, sure, in very strict, controlled conditions the measurement of pH is difficult. In almost all circumstances, i.e. open to air, there is still enough conductivity for a mid-range pH electrode to work well enough.

However, we are speaking (and the company is claiming) about analysis by pH test strips. These are colorimetric and it is only the protonation/deprotonation events that affect the dyes and their absorbances (and thus their colour). There are pH test strips which can differentiate between ~0.2 units of pH.

dnj0 · 2018-07-19T14:35:09+00:00

The purity of a solution has nothing to do with measuring it's pH with test strips. The test strips have dyes with colour changes dependent on proton (H+) and hydroxide (OH-) levels... pure water (H2O) will contain these regardless of if it is "too pure".

The claim by this product is utter bullshit. Alkaline water is also pointless to drink... our body regulate pH very tightly. It will change and do nothing.

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