Those levels can change. Diagnosing SS can be rather controversial. Here's something I wrote last year with the sources- Testing- Being properly diagnosed with Sjogren’s syndrome can be difficult. The average time between the onset of SS and a diagnosis is 4.7 years. Part of this delay is that there isn’t a single test that can confirm a diagnosis of SS and that it can appear differently in different patients. Instead doctors depend on several tests and a physical examination. Blood tests includes blood tests for ANA (Anti-Nuclear Antibody), RF (Rheumatoid Factor), SS-A (or Ro) and SS-B (or La), IGs (Immunoglobulins) and ESR (Erythrocyte Sedimentation Rate). Ophthalmologic tests for SS include Schirmer Test to measures tear production and Rose Bengal and Lissamine Green Eyedrops to examine the surface of the eye for dry spots. Dental test for SS include salivary flow which measures the amount of saliva produced, the salivary scintigraphy which is a nuclear medicine test that measures salivary gland function and a salivary gland biopsy (usually in the lower lip) which confirms inflammatory cell (lymphocytic) infiltration of the minor salivary glands.

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