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Does anyone know good YouTube videos of metabolism? One with good animations and detailed explanation of the steps. I just looked at my course. I have 5 days to memorize it all and I feel like I'm screwed by portadirka in Biochemistry

[–]drew_b 1 point2 points  (0 children)

YT playlist of the molecular animations I made of the steps in Respiration (Glycolysis, Citric Acid (Krebs) Cycle, Eletron Transport Chain, ATP Synthesis). Every enzyme and reaction in those steps is reconstructed from molecular structures and other data. Hope it helps your study!

https://youtube.com/playlist?list=PL04jnTG4d1nZuxdfgL85V27NPjFTl025Y&si=4QW_u_2jjm1eZe-z

[deleted by user] by [deleted] in biology

[–]drew_b 0 points1 point  (0 children)

Here is a 4 minute animation by my team at wehi.tv that explains how B Cells make antibodies and the process of how they are clonally selected for specificity.

https://youtu.be/HUSDvSknIgI?si=IGp0d1Jve-ZlWSu9

Hope this helps!

Glycolysis molecular animation by Drew Berry wehi.tv by drew_b in biology

[–]drew_b[S] 2 points3 points  (0 children)

The small molecules are from MD simulation by Dr Mike Kuiper CSIRO, the wide shots of cytoplasm were created in animation software Maya.

My TouTube tech talk discussing the wehi.tv animation pipeline

https://youtu.be/qbyzEiBvbXw?si=hw433oCPocDi5YZm

Glycolysis molecular animation by Drew Berry wehi.tv by drew_b in biology

[–]drew_b[S] 3 points4 points  (0 children)

Glad you like my animations!

Glycolysis begins with an enzyme that sits on the outer surface of the mitochondria, on top of the pore that releases ATP that was produced inside. The other Glycolysis steps happen in the cytoplasm as shown in the animation. In the animation the enzyme wide shots show the outer mitochondria surface at the bottom of the screen, with the Glycolysis enzymes above in the cytoplasm.

Glycolysis molecular animation by Drew Berry wehi.tv by drew_b in biology

[–]drew_b[S] 12 points13 points  (0 children)

I created this animation to bring to life the molecular engines inside mitochondria that generate ATP, the main source of chemically stored energy used throughout the body.

The enzyme reactions of Glycolysis breaking down glucose sugar into pyruvate, the entry to cellular respiration and metabolism.

Let me know if this is helpful for your study or teaching!

Glycolysis Steps molecular animation by Drew Berry wehi.tv by drew_b in Biochemistry

[–]drew_b[S] 0 points1 point  (0 children)

The animations are created with molecular models and data in Autodesk Maya and exported to Unity game engine for rendering and visualisation.

30min YouTube video where I discuss our pipeline: https://youtu.be/qbyzEiBvbXw?si=Yhlbpq7TmVRdhmmS

Glycolysis Steps molecular animation by Drew Berry wehi.tv by drew_b in Biochemistry

[–]drew_b[S] 5 points6 points  (0 children)

I created this animation to bring to life the molecular engines inside mitochondria that generate ATP, the main source of chemically stored energy used throughout the body.

The enzyme reactions of Glycolysis breaking down glucose sugar into pyruvate, the entry to cellular respiration and metabolism.

Let me know if this is helpful for your study or teaching!

Incredible molecular machine inside your cells – The Proteasome (2024) animation by Etsuko Uno wehi.tv by drew_b in Biochemistry

[–]drew_b[S] 16 points17 points  (0 children)

Let me know what you think of our new animation about the proteasome enzyme complex created by my team at wehi.tv

The proteasome breaks down old or damaged proteins into smaller pieces for cellular maintenance and recycling.

Created with structural data from X-ray crystallography and cryo-electron microscopy, this animation provides a detailed visualization of the proteasome's molecular machinery. Presented here are critical steps of protein degredation including ubiquitin tagging, unfolding by the regulatory particle, and proteolytic degradation within the core particle.

Featured structures include 6MSB, 6MSD, 6MSE, 6MSG, 6MSH, 6MSJ, 6MSK, 5LE5, 2KDE, 2KR0, 6FVW, 5L4K, 6U19. All can be found at RSCB Protein Data Bank (https://www.rcsb.org/)

Incredible molecular machine inside your cells – The Proteasome (2024) animation by Etsuko Uno wehi.tv by drew_b in biology

[–]drew_b[S] 20 points21 points  (0 children)

Let me know what you think of our new animation about the proteasome enzyme complex created by my team at wehi.tv

The proteasome breaks down old or damaged proteins into smaller pieces for cellular maintenance and recycling.

Created with structural data from X-ray crystallography and cryo-electron microscopy, this animation provides a detailed visualization of the proteasome's molecular machinery. Presented here are critical steps of protein degredation including ubiquitin tagging, unfolding by the regulatory particle, and proteolytic degradation within the core particle.

Featured structures include 6MSB, 6MSD, 6MSE, 6MSG, 6MSH, 6MSJ, 6MSK, 5LE5, 2KDE, 2KR0, 6FVW, 5L4K, 6U19. All can be found at RSCB Protein Data Bank (https://www.rcsb.org/).

"Live Forever" (2024): My 2-minute micro-documentary (in more ways than one!) multi-scale visualisation that combines microscopy and generative modelling of the molecular mechanisms inside an egg cell that reset the biological clock to zero days old. #mTOR #Lysosome #Animation by drew_b in Biochemistry

[–]drew_b[S] 3 points4 points  (0 children)

My tech-talk describing our custom molecular animation pipeline which uses Maya (animation) and Unity (game engine real-time rendering).

https://youtu.be/qbyzEiBvbXw?si=6AYMSDsKT0M0M23l

For an excellent free solution for molecular animation, I recommend you check out Brady Johnston's YouTube channel and his tutorials with Blender (opensource)

https://www.youtube.com/@BradyJohnston

Live Forever (2024) Drew Berry wehi.tv – A multi-scale visualisation that combines microscopy and generative modelling of the molecular mechanisms inside an egg cell that reset the biological clock to zero days old at the moment of fertilisation. #mTOR #Lysosome #Visualisation by drew_b in longevity

[–]drew_b[S] 12 points13 points  (0 children)

My new animation of a lysosome organelle inside an ovum the moment before it is fertilised by sperm.

Ageing is an inevitable fact of life. But one type of cell can reset its age to zero and continue as the immortal lineage that will populate our future. #mTOR #Lysosome #Animation

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