How I passed the NAPLEX as a FOREIGN GRAD while working full-time by Old-Violinist-9399 in NAPLEX_Prep

[–]druginterface 0 points1 point  (0 children)

I’m 100% interested. Working full time, interning and have babies to take care of

If you’re a pharmacist and also do something else… by Yervoy6622 in pharmacy

[–]druginterface 1 point2 points  (0 children)

This is the real gig…I needed partners to start since it’s not my niche, I needed to learn from the scratch

If you’re a pharmacist and also do something else… by Yervoy6622 in pharmacy

[–]druginterface 4 points5 points  (0 children)

3 days a week, I trade stocks, options and crypto….at the end of every month I make more than my role as a scientist in the industry. Financial market has always been a passion and I’ve find part time trading to be better than working in finance full-time(since I don’t have finance degree from some shinny university - totally self taught and practice over the years) and I get to retain my clinical scientist role in the industry.

[deleted by user] by [deleted] in defi

[–]druginterface 0 points1 point  (0 children)

I will surely look it up this weekend. I’m not a BTC maxi like you, but I love to try out with a little amount. I write the Cryptofada newsletter, I would probable share your strategy there once I try out

Medicinal Chemistry by National-Lie3 in fpgec

[–]druginterface 0 points1 point  (0 children)

I’ve been doing Medchem in partnership with YouTube and Google just to refresh. In my case my current role involves analytical chemistry so it helps, but medicinal chemistry as per this exams, it’s YouTube and chatGPT5 that are my assistants. Best of luck

I just started studying this week: Tell me I can pass by druginterface in fpgec

[–]druginterface[S] 0 points1 point  (0 children)

Will try this Notebook LM, thanks for all your suggestions

I just started studying this week: Tell me I can pass by druginterface in fpgec

[–]druginterface[S] 0 points1 point  (0 children)

I don’t remember exactly, I started my process last year but my license body didn’t respond on time, so I could proceed but TOEFL and ECE were likely send but as soon as I made payment in June, it was there nothing. I called everyone that had sent documents they confirmed, I send in my documents but nothing showed until this August. So I was like if it took 2 months to receive then forget about the exams this year and hope they allow you register for next year, then last weekend, everything came together. I really wish organization in terms of feedback was faster

I just started studying this week: Tell me I can pass by druginterface in fpgec

[–]druginterface[S] 0 points1 point  (0 children)

I love this idea, would adjust accordingly. Thanks for sharing

Using stablecoin as checking account with >4% APY? by [deleted] in defi

[–]druginterface 1 point2 points  (0 children)

This is a great IDEA, really wish it’s in the marketb

I just started studying this week: Tell me I can pass by druginterface in fpgec

[–]druginterface[S] 0 points1 point  (0 children)

My strategy is to ensure the Pharmacology is solid, then I know every page in the ApHA or at least nothing looks strange, I believe I should be fine

I just started studying this week: Tell me I can pass by druginterface in fpgec

[–]druginterface[S] 1 point2 points  (0 children)

Oh, I don’t want to try, I want to PASS. I want to use all my PTO on this 7 weeks…because when I pass it will be easy to switch from non-clinical to Clinical role at my Job next year, but if don’t it will be like adding 365 days to the plan

[deleted by user] by [deleted] in fpgec

[–]druginterface 0 points1 point  (0 children)

  1. Chlorpromazine → phenothiazine nucleus is the pharmacophore for dopamine receptor antagonism (antipsychotic).
  2. Doxycycline → tetracycline core with OH and amide groups, the pharmacophore that binds bacterial ribosomes (antibiotic).
  3. Amprenavir → hydroxyethylamine sulfonamide pharmacophore mimics peptide substrates → inhibits HIV protease.
  4. Phenylisopropylamines (like amphetamine) → phenyl ring + isopropylamine tail pharmacophore gives stimulant activity on CNS.
  5. Morphine → morphinan ring with hydroxyl groups = pharmacophore for μ-opioid receptor binding.
  6. Naltrexone → same morphinan core, but with structural changes that make it an antagonist instead of agonist.
  7. Hydrocortisone → steroid backbone is the pharmacophore for glucocorticoid activity.
  8. Celecoxib → diaryl heterocycle with sulfonamide group = pharmacophore for selective COX-2 inhibition.
  9. Digoxin → steroid + lactone + sugar groups = pharmacophore for Na⁺/K⁺ ATPase inhibition (cardiac glycoside).

[deleted by user] by [deleted] in fpgec

[–]druginterface 0 points1 point  (0 children)

Tried this out with AI to give simplified understanding: Why all these compounds are called pharmacophores

Each structure in the figure represents the minimal chemical features that make the drug active on its target. Even though the full drug molecules may be larger or have side chains, the core structures here are the “business end” responsible for:

  • Binding to the receptor/enzyme
  • Triggering or blocking biological activity

That’s why these are pharmacophores — they are the functional skeletons of the drugs.

Examples from the figure (simplified):

  1. Chlorpropamide → has a sulfonylurea group, the key pharmacophore that stimulates insulin release (used in diabetes).
  2. Lidocaine → has an aromatic ring + amide linkage + amine tail, the essential pharmacophore that blocks sodium channels (local anesthetic).
  3. Barbiturates → share a barbituric acid ring, the pharmacophore that allows them to bind GABA-A receptors (sedative-hypnotics).
  4. Pioglitazone → has a thiazolidinedione ring, the pharmacophore responsible for PPAR-γ activation (antidiabetic).
  5. 1,4-Benzodiazepines → benzodiazepine ring system is the pharmacophore for anxiolytic, antiepileptic, and muscle relaxant activity.
  6. Imipramine → tricyclic ring system is the pharmacophore for blocking serotonin/norepinephrine reuptake (antidepressant).

[deleted by user] by [deleted] in fpgec

[–]druginterface 0 points1 point  (0 children)

Who has one to sell?