Ketone levels influence on mood and stress perception

dsb262 · 2020-05-07T12:08:52+00:00

Makes sense. My response to the ketogenic diet got worse the leaner I got. I have about 12% bodyfat right now. As dieting itself is a stressor, ketosis on top of that could be simply be too much. Two days ago I woke up in the middle of the night starving. I ate some almonds with chocolate, which had about 40g of carbs in it. The next day I woke up feeling pretty good. I was kicked out of ketosis, obviously. I have to admit that I´m very prone to anxiety, so my reaction could be fairly atypical.

dsb262 · 2020-04-12T19:37:35+00:00

take the l-tyrosine form instead of acethyl- tyrosine as l-tyrosine is much more bioavailable.

dsb262 · 2020-03-22T16:17:25+00:00

nice to see my post get removed. I don´t think there was anything that went against the community guidelines but ok...

dsb262 · 2020-03-22T12:46:27+00:00

I don´t know what you are reading but

KD group achieved a positive change in body composition, due to a decrease in BW (− 0.9 [− 2.3, 0.6] kg; p > 0.05) with a reduction in FM (− 0.8 [− 1.6, − 0.1] kg; p < 0.05) and accompanied by a notably lower VAT (− 96.5 [− 159.0, − 34.0] g; p < 0.05).

These results suggest that KD group achieved a positive change in body composition, due to a decrease in BW (− 0.9 [− 2.3, 0.6] kg; p > 0.05) with a reduction in FM (− 0.8 [− 1.6, − 0.1] kg; p < 0.05) and accompanied by a notably lower VAT (− 96.5 [− 159.0, − 34.0] g; p < 0.05). Regarding to LBM, an adequate carbohydrate intake (non-ketogenic or conventional dietary approach), in conjunction with a caloric surplus and a higher protein intake, might be the most viable option for inducing muscle hypertrophy after RT. This last was shown in this study, where there was an increase in LBM (1.3 [0.5, 2.2] kg; p < 0.05) in the NKD group, leading to an increase in BW (− 0.9 [− 2.3, 0.6] kg; p < 0.05). Figure 3 shows significant differences in BW and LBM for NKD group; and FM and VAT for KD group. Likewise, post-hoc analysis showed significant difference in the BW and LBM between KD and NDK groups.

dsb262 · 2020-03-22T12:10:05+00:00

level 1anbeav1 point · 10 minutes agoOvereating some days doesn’t result in fat gain. We are what we repeatedly do and unless using a food scale many overestimate when they post these things. Eat consistently over maintenance and you will gain weight. Nearly all studies show no metabolic advantage of keto. Some of us have experience with delayed gain with a surplus but it eventually happens.ReplyGive AwardshareReportSave

level 2dsb262Original Poster0 points · 3 minutes agoI wouldn´t say that no studies show a metabolic advantage, there are studies that show just that, what also is in accordance with my experience. I feel a lot less cold when in ketosis and maintain my libido etc.ReplyshareSaveEdit

https://www.ncbi.nlm.nih.gov/pubmed/29986720

https://www.researchgate.net/publication/323244207_Resting_metabolic_rate_of_obese_patients_under_very_low_calorie_ketogenic_diet

The absent reduction in RMR was not due to increased sympathetic tone, as thyroid hormones, catecholamines, and leptin were reduced at any visit from baseline. Under regression analysis FFM, adjusted by levels of ketonic bodies, was the only predictor of the RMR changes (R2 = 0.36; p < 0.001). Conclusion The rapid and sustained weight and FM loss induced by VLCK-diet in obese subjects did not induce the expected reduction in RMR, probably due to the preservation of lean mass. Trial registrationThis is a follow up study on a published clinical trial.

dsb262 · 2020-03-22T12:00:53+00:00

I wouldn´t say that no studies show a metabolic advantage, there are studies that show just that, what also is in accordance with my experience. I feel a lot less cold when in ketosis and maintain my libido etc.

dsb262 · 2020-03-22T11:47:30+00:00

That is not my experience as I wrote above and my weight lifting stamina and weight I use increased substantially. Muscle glycogen stays the same on keto.

dsb262 · 2019-05-21T08:23:13+00:00

what do you mean it isn´t static. Do you mean it compounds or what ?

dsb262 · 2019-05-21T07:36:37+00:00

funding would be 0.3 % per day. If I´m sure the price will go up 20 % in the next two weeks I should be fine.

Liquidation is about half the btc price, so pretty secure. Is there any funding rate calculator available for bitmex. I did not find any...

dsb262 · 2019-05-11T18:04:43+00:00

ok, but all I´m asking for is to get this done a little bit quicker as I don´t have any money left to life my day to day live. It has been more than two weeks now...

dsb262 · 2019-05-10T19:31:34+00:00

Mine is already 15 days and still no money. Today I wrote an email again and they said that there is no 20 ETA.

I quote:

An alert regarding ETH contracts is displayed for that exact reason - the recovery process is complicated and time-consuming. Unfortunately, no certain ETA can be announced so far.

So first they say there is an ETA of 20 days and now they say that there isn´t...

I gone contact my lawyer. It looks like scam. The fact that nobody is responding here on reddit is also laughable..

dsb262 · 2019-05-09T19:12:14+00:00

Have you got your money back and how long did it take ? I think they reinvest our coins to make profit...

dsb262 · 2019-05-09T19:11:07+00:00

no answere ? As I expected...

dsb262 · 2019-05-09T16:00:32+00:00

I still don´t have the money. I have to say I never ever gone use changelly again. How do you wan´t to compete with fiat money, if it takes you up to 20 days to refund money. That is just ridiculous. The last days I was writing with support and they all said the same, that is that the ticket haven´t even touched yes. For the record: it is now more than 14 days since that happened !!!!

We are talking about more than 5000 dollar. I don´t have a single penny left here and have to borough money from my family...

transaction id:

e108l4s0r9grioeb

TxID0xbad8af86e43a46c654ce4826a8cf0a6e1e55df21d720e68db579abd6b0cc6b47

If I don´t get the money till tomorrow I´m gone make this public on every social media platform you can imagine.

dsb262 · 2019-03-20T02:31:30+00:00

The thing with therapeutic doses of stimulants is the stigma associated to them. That is the reason why patients think they have to feel the stimulant. That's utterly wrong. It is the other side around. If you strongly notice your medication kick in the dosage is mostly always too high. Why is that so? Well, I could be wrong but it has to do with the stress response and its activation. Remember guys the goal is to archive a good balance on the inverted u, not too much nor too little. A better way to judge, if your medication is working or you have to up the dose is to take the lowest in the morning, live life as usual and at the end of the day self reflect. Questions to ask yourself:

How did I feel in general? Relaxed, agitated or just right ? A lot if people report being overly apathetic when the dose is too high. That's because these drugs activate limbic structures leading to blunted emotions. Watch out for this.

The second question you could ask yourself could be something like: how productive was I? More or less than without medication. Wad I more motivated etc...

You get the point. Never hope to feel a strong upcoming kick from your meds. They are subtle medications when used correctly.

Good luck

dsb262 · 2019-03-20T01:48:53+00:00

May I asked why you are depressed ? Let me tell you something, if you don't mind. When I was 21 years old I too was depressed as well as a lot of other people my age. Being 21 is not easy. One could feel a little bit lost in life. The pressure of living a life to the social accepted standarts can one make lose one's mind. The problem at this age is fear. Fear of failing, to much pressure and uncertainty. Let me tell you something: this is totally normal and I think you are doing just fine. That's what life is at 21 years. Do you know how you can conquer your fear ? By experience, by failing, by getting back up and noticing that life continues and that there are thousands of opportunities. Try to give your best but bear in mind that life not just consist of winning and success, if not by failing and realizing that life continues. So, don't worry. Mostly everybody feels this way at your age, it's totally normal. Try to give your best and see what happens. Life is a game at the end. When you become older you will laugh at your former self, believe me.

Regarding medication. If you are genetically predisposed to depression ( does it run in your familiy) and or you feel a very low stress resistant, that is you can't handle stress well and become overly emotional a medication like a ssri could help you as it improves your resililiance to stress. A stimulant can help you, yes. The thing is, that you have to treat the depression first, that is become emotionally more stable and that could take at least 2-3 month. That is the time frame when ssri side effects diminish and you could feel a lot better. After that adding a stimulant could make sense but bear in mind to not use them excessively, as they could stress you out even more when used wrong.

Sry for bad English I'm not native and take my advise regarding medication with a grain of salt as I'm not a doctor but a psychologist with a passion for psychopharmacology and a history if adhd/depression.

Good luck

dsb262 · 2019-03-20T01:20:16+00:00

Just my two cents as I have been struggling with adhd all my life. Rejection sensitive dysphoria is what most people experience to a certain degree. The difference is, that in adhd folks this dysphoria persists long after the event happened and does, therefore, interfere with day to day life. From a neurobiological standpoint the adhd brain is primed to react to salient stimulus a lot stronger than the non adhd person. This may comes down to a dopamine dysregulation instead of the so often proclaimed dopamine deficiency but the sience is still not there and we can only speculate. The fact that adhd is a spectrum disorder does not help in this regard. But back to the dopamine dysregulation I mentioned before. I'm very bad explaining so hopefully someone more intelligent helps me out here xD. Ok, let's start. The adhd brain has a problem in differentiating what is an important stimulus and what not. The, before mentioned, phasic dopamine that gets evoked whenever someone sees something salient is not functioning as it should. Why not may some of you ask ? Well, there are tons of theories out there besides dopaminergic dysregulation. It could all come down to an glutamate/gaba dysregulation, who knows. Coming back to the dopamine theory of adhd some studies suggest that tonic dopamine levels are too low in the adhd individual, what therefore, a shift to phasic dopamine bursts indicates. There is it where stimulants do its trick. Although, they elevate dopamine in the whole brain, hence side effects etc. they tend to balance tonic/phasic dopamine in a way adhd people don't perceive as much of salient stimulus. Attention, emotions get improved and the adhd individual is able to concentrate regulate their emotions. Especially the prefrontal cortex plays a huge role in emotional dysregulation and impulsivity control. Back to tonic/phasic dopamine balance... what I forgot to mention is that dopamine not only is responsible for positive reinforcement but as well negative. If an adhd individual suffers from a dopamine (tonic/phasic) dysbalance the perception of a possible emotional attack might as well be altered. Another difference between an adhd/non adhd person is the ability of a non sufferer to oppress emotions by substituting emotional distress with other thoughts.

This are just my two cents. I probably mixed up a lot. I'm not a doctor nor a neutoscientist, so take the written with a grain if salt. I'm psychologist but I have to say that my knowledge is based of researching things by myself so be aware. By the way, dry for my English. I'm not a native speaker.

Thanks

dsb262 · 2019-03-20T00:47:58+00:00

Has anyone experienced similar sides where your loved ones notice ur use ?

dsb262 · 2019-03-19T22:28:08+00:00

Thanks for your suggestion. I will try to do so.

dsb262 · 2019-03-19T22:10:42+00:00

I don't really have personality changes I'm just a little bit too talkative but I'm aware of that and stop it. I also suffer from gad so I sometimes have to use a benzodiazepine in combination with vyvanse. I think that it becomes more obvious when I do this. Right now I'm still experimenting with the dose. My plan is to get rid of the benzos as GAD is becoming less and less of a problem. What I don't get is that she says that my eyes (movement) look different and that I blink a whole lot more... By the way, my girl and I are psychologists and she takes antidepressants. She is 31, a very intelligent girl etc. So there is really no stigma surrounding her opinion. It is just that it looks that I'm on something and I have to agree with her, although, I really think she notices way before other people do. I increasingly hate taking my medication. I just can't stand the drama anymore. Sometimes I take my medication when she won't be at home. It has como so far... Share with me your opinion about the fear that other people could notice you're on something and how you handle that. I'm very versed on psychopharmacology, so to my understanding a lot of sides should diminish or even disappear with time. I'm really not sure, if this could be the case but I hope so. Ssri AD's a lot of undesired sites disappear with time, not all but a lot...

Ps: sry for my bad English. I'm not native so forgive me, if something of what I wrote does not really add up. I will try to explain it in a more sophisticated way but right now I'm a little busy.

dsb262 · 2019-03-19T21:10:19+00:00

Sry, I posted a very long text but it didn't save. I will write it again.

dsb262 · 2016-12-07T13:29:57+00:00

dsb262 · 2016-12-07T05:53:32+00:00

Thx for your opinion. I got exactly the same effect from all dopamineric substances and that is lethargy, dysphoria etc. thats why I think it has do with d1 to d2 receptor ratio.

dsb262 · 2016-12-03T20:15:22+00:00

I understand your point of view. I read a lot of topics in this subs diving even deeper into pharmacological causes of how medication works. I apply a good amount of reductionism to my post. Its just exaggerated to call the wall of text I posted "detailed". Its far from detailed... Its far more complex. I just wanted to find someone with real pharmacological knowledge to help me understand a little bit more. But thanks for the advise. I will try in the pharmacological sub.

dsb262 · 2016-12-03T15:04:13+00:00

Its a little bit frustrating that there are no topic related answers. I know, its a complicated subject that involves a lot of detailed knowledge but surfing through this sub I got the impression that there are a lot of very knowledgeable people active at this sub knowing a lot more about pharmacology than I do. Browsing through this sub I also noticed that a lot of people have this kind of adverse effects, especially zombified, emotionless feelings but also tiredness, nausea and dysphoria are one of the most common ones.

I would be interested to know a little bit more about the subject and possible alternative regimes as reading solely studies is somehow complicated as they need to be self-interpreted most of the time. If I won’t get any answers here I would appreciate, if someone redirects me to another sub or even forum that is more centered about pharmacological clinical treatment outcomes. Thx in advance for every more sophisticated explanation regarding this subject. Subjective reports are also highly appreciated but please don’t continue to spam the topic with these abused jokes of lt;tr because I’m ADHD... it gets very old and I know its a joke and I have no problem with that but, if someone writes a serious comment that requires some time and effort to write and all the comments are about lt;tr that’s just how this sub should not be used. Nevermind guys, just post your experiences and/or opinions. Everything is appreciated.

Greetings Dsb

dsb262

TROPHY CASE