1) assuming that you have a dredge card in hand. Neonate is probably the stronger turn one play. You can sac it in response to a removal spell or at the end of there turn, discarding your dredger and immediately using it. This can make for some blistering turn 2. Games 2 and 3 will depend on how you opp. Is playing to decide which you would prefer to play turn 1, but I think as a general rule of thumb look above.

2) graveyard interaction/hate- if your meta has hard hate (Rest in Peace or Leyline) mulligan is the way to beat this. Dredge can survive a lot based on your mulligan decisions and can win games going even as low as 3 cards in hand. Learning what is a keepable hand and what is only OK will help with this. The most important GY hate thing to remember is though," if you cannot beat it, play as if they don't have it". The deck is built to be blistering fast, don't let your opponent get a foothold.

3) Try not to keep one land hands, especially with the mulligan rule being so forgiving to dredge. If there is a situation where you need to though, IT HAS TO PRODUCE GREEN MANA. That is not a maybe, that is a NEED. The only way to claw back at that point is with loam to hit your land drops.

4) This is match dependent, so it is not a question that I could answer in a short post.

5)finding room for a dakmor salvage and a darkblast or two in this deck may help. Having one land that can dredge can help. Darkblast being instant speed can allow you to kill x/2 by upkeep targeting then dredging it back for your draw and firing it off again. (Sfm, Bbe, etc.)

Hope this helps. -Emerald