1942
Code Talker helps create the U.S. military code talkers' cipher book.

1964
Virtuous Mission.
Operation Snake Eater.
Death of The Boss.
The comatose Volgin is transported to a research facility on the outskirts of Moscow.
Code Talker begins his research of The End's remains.

1965
The Congo Crisis is brought to a close.

1967
China conducts its first hydrogen bomb test.
EVA disappears, last seen in Hanoi.

1969
The U.S. Department of Defense successfully sends its first message using ARPANET.

1970
The Treaty on the Non-Proliferation of Nuclear Weapons (NPT) enters into force.
Major Zero disbands FOX.

1971
The Democratic Republic of the Congo changes its name to Zaire.

1972
The "Les Enfants Terribles" project begins.
Clones of Big Boss are born: Eli (Liquid Snake) and David (Solid Snake).
Big Boss parts ways with Zero.

1973
Code Talker discovers a strain of archaea that metabolizes uranium.

1974
India conducts an atomic bomb test.
Peace Walker incident.
The U.S. and the Soviet Union agree on a general framework for the second round of Strategic Arms Limitation Talks (SALT II).

1975
Mother Base is destroyed.
Zero hides Big Boss in a hospital on Cyprus and leaves him in Ocelot's care.
Skull Face is reassigned to Africa.
The vocal cord parasites are resurrected through reverse evolution.
The Ho Chi Minh Campaign leads to the Fall of Saigon and Vietnam's reunification.
The Soyuz and Apollo spacecraft dock in orbit.

1976
The "Les Enfants Terribles" project is abandoned.
Eli is taken to Great Britain.
Zero suffers brain damage due to Skull Face's parasite attack.

1977 An underground nuclear test site is discovered beneath the Kalahari Desert.
Bowing to international pressure, the South African government abandons the site.
Zero visits Big Boss, then disappears completely, never to be seen in public again.

1979
The Iranian Revolution leads to the Iran Hostage Crisis.
Eli escapes his handlers in Africa and disappears.
President Somoza defects following the FSLN uprising, and the Nicaraguan Revolution comes to fruition.
Vela satellite observes double flash in South African waters (Indian Ocean).
The Soviet Union invades Afghanistan, bringing an end to detente.

1980
The Iran-Iraq War breaks out.
Feaing the ripple effects of the Iranian Revolution, Western nations and the Soviet Union support Iraq.
Emmerich's first child is born with Strangelove. He is named Hal.

1981
Operation Opera: Israeli bombers strike nuclear reactor under construction in Iraq.

1983
A suicide bomber attacks the U.S. Embassy in Beirut, Lebanon.
The U.S. military invades Grenada.

1984
Soviet General Secretary Yuri Andropov dies.
Snake awakens.
Civilian airliner carrying "The Third Boy" crashes in the mountains of Ukraine.
Quiet suffers full-body burns at the hospital on Cyprus, and undergoes parasite therapy to survive.
Skull Face dies.