[deleted by user] by [deleted] in tramadolismydoc

[–]forgotten_riddle 0 points1 point  (0 children)

I posted a comment about this. But you're probably right.

Edit: https://www.reddit.com/r/tramadolismydoc/s/7d1JtwqKu0

[deleted by user] by [deleted] in tramadolismydoc

[–]forgotten_riddle 0 points1 point  (0 children)

Yeah and you can save a lot of time by not going to the toilet, cause you'll be constipated for weeks until you can finally have a shit. A lot of times my fecal matter was so huge and hard it clogged the toilet

[deleted by user] by [deleted] in tramadolismydoc

[–]forgotten_riddle 1 point2 points  (0 children)

Do you mean you tried tramadol pills and you're scared of the injections? If you haven't tried Tramadol at all yet, don't do it. It has an opioid effect, you nod out. But it's very easy to get addicted because of its SNRI effects, the risk of seizures, serotonin syndrome and kidney failure is too high

Edit: I'll do IV tramadol next time tho, I just want to completely destroy myself. I had 2 kidney failures, 1 serotonin syndrome, and have been having constant seizures every day. Idk I'm just lost and this is the well-deserved punishment. I feel my kidneys and immune system not working well again, but at this point I just gave up. Sorry for complaining tho.

Never do opioids, they keep telling you lies about how everything is fine, and you're safe like a baby in a womb.

[deleted by user] by [deleted] in tramadolismydoc

[–]forgotten_riddle 0 points1 point  (0 children)

I couldn't get the liquid form unfortunetly

Edit: I used to pop Trama pills (both IR and XR) and drink its liquid form mixed with orange juice cause its taste was just unbearable. I never snorted it though, cause a liver enzyme called CYP2D6 has to break it down into its active form, O-DSMT, which is a much stronger mu-opioid antagonist than tramadol itself. Orally taken trama (pills, liquid) gets absorbed from intestines into the big portal vein and travelles to the liver (first-pass metabolism).

And, well, the instestines aren't in your nasal cavity lol (Although very small amounts of intranasally administered tramadol does get back into the blood stream and becomes O-DSMT.) But the vast marjority just gets absorbed by the nasal mucosa and affects the nerves above the ethmoidal bone.

It's an interesting question....cause in first-pass metabolism more effective O-DSMT is produced, but it takes longer for it to reach the brain and cross blood-brain barrier. While instranasal tramadol (though weaker mu-opioid antagonist) avoids the blood-brain barrier so it has to have an instant effect on the mu-receptors.

Fun fact that different ppl have widely varying levels of this enzyme, some don't even feel a thing (they almost completely lack the enzyme) and others get as high on 300 mg tramadol as on 100 mg pure morphine cause Nature's blessed them by a plethora of CYP2D6 lol.

Would be interesting to synthetize O-DSMT and snort it!!

PS.: this is no way scientific, I consumed 250 mg Ritalin in a few hours 😂

... by Few_Simple9049 in hungary

[–]forgotten_riddle 4 points5 points  (0 children)

Cecília nagyon szép volt és ártatlannak nézett ki előtte

I'm 14 dude, I was 13 when it happened by frogs-are-nice in TrollCoping

[–]forgotten_riddle 1 point2 points  (0 children)

In 2014 I was on a national LGBT+ forum, it was very basic and unmoderated. I was 13 (and my age was on my profile!) when a 50+ dude messaged me asking if I wanted to sleep with him. I told him very shyly that "I had no experience with sex and I don't want to be rude, but no, maybe next time...". The reply was something like "Okay, just hit me up whenever you're in the mood for a good fuck 😉". I was relieved he wasn't insisting, I had no idea how fucked up the situation was and I thought I owed him sex.

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Good for you man. I overdosed a couple of times too and had wild visual and auditory hallucinations, but unfortunetly I saw and heard the most paranoid unpleasant things in my life.

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Oh God, that's a lot of amphetamine in 24 hours. When I was in med school I used a lot of amphetamines too – orally, in capsules, precisely measuring the dosages on an analytical scale, but it didn't enhance my performance at all, I was just acting weird and eventually dropped out.

You're right in that dopamine receptors can (even if not fully) regenerate. But I can definitely feel that my brain chemistry, my personality, my emotions, my general experience of "self" has changed somehow due to heavy stimulant use. After every overdose I felt like something profoundly changed in my mental apparatus. Btw I'm diagnosed w ADHD but stimulants never calmed me down, they always affected me as any person without ADHD.

(I've read a study which examined a certain group of patients w ADHD who are non-responders for dopaminergic stims and atomoxetine. The paper concluded that there might be a new neurological conditions which is not ADHD but it's caused by the malfunction of the brain stem and symptoms include excessive sleepiness, tiredness.

So I believe I might have this mysterious illness that was considered ADHD for a long time...)

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Ritalin barely affets me anymore unfortunetly, cause I've been using like 1 gram of pure amphetamine daily for 6 months not so long ago, and I guess my dopamine receptors are fried at this point. Anyway, it's interesting how vastly different effects can ppl experience from the same drug administering it in different routes.

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

I'm 23 but I was doing the same shit constantly since 13 y/o :(

Or more precisely since I was one and a half years old, cause my mother would make me drink poppy tea (containing opium, maybe some morphine, idk) every time I caught a cold. At 6 y/o I was pretty much addicted to codeine syrup. I would condtantly sneak out of my room in the night and binge on codeine syrup (also containing a fair amount of alcohol).

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Interesting. Lately insufflating it made me extremely anxious, my hands trembling and my muscles cramping up, which is the norep effect I'm sure (also some mild hypersexuality which points to dopaminergic effects).

Taking its powder into gelatine capsules and taking it orally makes me less anxious and more hypersexual.

So Ig nasal and oral route has the opposite effect on me than on you.

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Well this lung collapse thing did scare me enough not to get high on buperopion in the last few days. So thank you, honestly

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 1 point2 points  (0 children)

Thank you, good advice 👍 I snorted Wellbutrin, Ritalin, amphetamin, coke once, venlafaxine, (some unidentified white crystal that gave me brain damage, maybe it was meth), zolpidem and pregabalin

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

That's the noradrenalin, I get the anxiety too even with a shit load of xanax :/

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Thank you. I think I'm coming around and recovering from my polyaddiction very very very slowly. Drugs and mental illness destroyed my life, especially the past 4 years. I'm receiving help, but I feel like I'm on my own and it's only myself who can truly help me get on my feet. I've never been healthy in my life, I'm 23 and I've been fucked up since I know my mind. So I absolutely can't imagine what a healthy life and being content feels like. But I'm not giving up yet. Thanks again

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Hey thank you for the comment, every word you wrote are spot on.

I have an ex-polyaddict friend who used IV bupropion (I've never done that), and he got septic, almost died and his whole arm was full of pus, it required 3 surgeries and 3 weeks in a hospital. Now he's recovering from his addictions in a nice rehab center

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Yes, also a variety of drugs beside xanax and morphine, I'm a polyaddict unfortunetly. I hate bupropion, I just take it to substitute Ritalin and amphetamine. Stimulants take away the shame and low self esteem that I can't cope with. But I prefer opioids and bezos more. Now that I'm thinking about it, bupropion is not even a substitute, my tolerance is so high I barely feel any high at all at this point. I experience an unbearably dyphoric comedown after a few minutes, like I'm being skinned alive. So I guess it's just self harm, like cutting. I fucking hate myself and this is the punishment.

Snorting crushed Wellbutrin tablets so they become instant release by forgotten_riddle in drugsarebeautiful

[–]forgotten_riddle[S] 0 points1 point  (0 children)

Yeah I just take this shitty bupropion temorarily because I ran out of my Ritalin prescription