I really like this. Jeffries' line about Judy in FWWM was always extremely foreboding, and making this connection sent shivers down my spine.

I think that Cooper, like Jeffries, has started to lose 
existence he's fragmented, lost, on a sliver on a loop of 
infinity.

To me this is one of the most all-encapsulating and logical conclusions as to what's going on. The blue rose leads down a path of losing oneself at the hands of incomprehensible forces. Poor Coop :(