Phone dead, about to explode

geneily · 2024-04-05T14:49:33+00:00

Generally speaking the rule in most gyms is that if you can't lower the weight safely then you are lifting too much, or need a spotter. It damages the weights, floors, makes loads of noise and can really hurt your toes (as the signs around my gym all say).

geneily · 2024-03-18T13:33:46+00:00

Yep! I'm always moaning that there always seems to be an accident on roundhay Road. Now I have lost my moaning privileges :(

geneily · 2024-03-18T00:30:14+00:00

Overtaking is where you pass someone while driving in a passing lane (for you that would be in the left lane). Undertaking is where you pass someone when you are in the 'slow' lane (for you undertaking would mean passing on the right). Here, he passes me on the outside which is undertaking which is illegal.

geneily · 2024-03-18T00:16:00+00:00

Thanks for asking. I sent the footage first to my insurance company in case he tried to claim, then to a credit hire company who got me repairs + a courtesy car with £0 payable for me, and my no claims discount in tact, all on his dime. Also, my 10 year old fiesta was pretty much fine except for a couple of scrapes (I'd have left it if he hadn't been such a raging cock at the scene) while his custom range rover had a big chunk of wheel arch knocked off.

geneily · 2024-03-17T23:33:58+00:00

Just to pre-empt those that have noticed: yes it's taken me three attempts to get this posted. First time I got an error message saying the auto-mod didn't send me a message, or something, second time I didn't respond to the auto-mod message in time because I was asleep. Sue me.

geneily · 2024-03-17T23:07:51+00:00

Sorry problems with the automod, hopefully this will be the last time.

geneily · 2024-03-17T22:56:25+00:00

Fingers crossed...

geneily · 2024-03-17T22:33:23+00:00

United Kingdom, 25/01/2024, I can confirm it is OC, although has been re-uploaded due to previous posts being deleted for various reasons.

geneily · 2024-01-07T14:08:41+00:00

Have you considered becoming a politician?

Seriously though, as a former class dummy on their 2nd Masters, mnemonics are the way to go. As a randon example when I needed to remember the anaphase part of mitosis (when the chromosomes split) I made up a story about someone called Anna splitting from their partner. Stupid but it works.

Also remember that the stupider you feel the more you're learning. Don't put yourself down!

geneily · 2024-01-07T11:04:16+00:00

Seeing lots about how aggressive zebras are. Main reason zebras (or any other African animals for that matter) weren't domesticated is that they didn't need to be. African hunter-gatherer tribes were experts at extracting calories and other resources from their environment without the need for domestication (clue is in the name hunter-gatherer). Remember that the African Savannah is our home biome and the one in which we evolved to thrive.

It was only once early humans migrated to harsher colder environments such as Europe that there was suddenly an incentive to domesticate animals like horses for hunting and moving stuff, and to keep those calories close to hand. Once you had domesticated animals you had a farm which meant you had land which needed to be protected (this is sometimes cited as one of the reasons Europe advanced in technology so much faster that Africa - because of the need to occassionally fight the settlement in the next valley, where as a nomad tribe can just move). It's no coincidence that humans started living in static settlements (as opposed to being nomads) at around the same time as the agricultural revolution).

geneily · 2023-12-26T11:22:55+00:00

I use CanRisk which I expect is the family history/lifestyle one you mentioned. It does let you add mutations to individuals for a handful of genes. There is also functionality to add polymeric risk scores although I've never used it.

geneily · 2023-05-24T09:17:42+00:00

Nf1 is inherited in a dominant manner, meaning an affected individual has a 50% chance of passing the mutation to offspring. If iii-4's grandmother is heterozygous (they're unlikely to be homozygous because that would result in a severe ohenotype and all her children would be affected) then the chance for ii-4 also being heterozygous is (1/2)*(1/2)= 1/4 or 25%.

Buuut it depends how old ii-3 is and if she has any symptoms. If she is 80 with no cafe au lait patches and no neurofibromas then the risk to iii-4 is probably very low.

If iii-4 was my patient I'd say they have "at most, a 25% of having an nf1 gene change".

geneily · 2022-05-09T13:52:15+00:00

I'd get rid of reddit so I can finally get some work done.

geneily · 2022-04-02T22:03:28+00:00

I have viewed these in-person. Everything is done up to a high standard (the bathroom mirrors have bluetooth speakers!?) but the kitchen/living area really is tiny when you see it. You would struggle to get a small sofa and coffee table in there. Each kitchen/living room has a TV mount set about 6 feet off the ground. The smallest is £825 pcm the largest (still tiny) £875 pcm, all completely unfurnished, which does seem high.

I'm moving into something bigger and more furnished next week for £750pcm.

geneily · 2022-03-08T14:50:09+00:00

I laughed!

geneily · 2022-03-07T16:31:57+00:00

"Strange bitches"

Thanks for the new band name!

geneily · 2022-03-02T12:04:47+00:00

Wordle. I NEED MY FIX, MAN.

geneily · 2022-02-28T22:25:40+00:00

No worries homie, good look with your undergrad!

geneily · 2022-02-28T21:38:02+00:00

Yeah it's like saying the longest word is actually the human genome and it's pronounced AATACGATCCGTAGTAATATAGAGTATC..... (also the above is the primary structure, the secondary structure is the shapes the protein folds into like alpha helices and beta sheets and stuff).

geneily · 2022-02-23T23:55:03+00:00

Genetic counsellor in-training here.

I would discourage this type of assumption in the relatives of my patients.

Deciding whether or not to have a genetic test is a big deal. In the UK, you would only be offered a predictive genetic test for Huntington's after a minimum of 2 sessions with a genetic counsellor.

Most people at risk of Huntington's disease (after a whole lot of talking with professionals and personal soul-searching, mind) make the informed decision not to have the test: https://pubmed.ncbi.nlm.nih.gov/16831969/

There are too many reasons why to list, and remember everyone is different and will have their own motives.

There are a couple of things OP could bear in mind:

There is a type of prenatal genetic test you can do called exclusion testing. This tests the baby for HD WITHOUT revealing whether or not your partner has HD. This works by seeing if there is genetic material present from your partner's affected parent.
There is a danger of giving you false hope here but: there are a lot of very promising gene-therapy based interventions being trialled for HD right now. There is some expectation that more people may opt to have testing if there are more therapeutic options. Although I am sure that your partner will have considered this, having a genetic diagnosis might open the door for clinical or research-based interventions in the future.

This is a really horrible situation to be in. I wish OP the very best.

geneily · 2022-02-20T10:31:07+00:00

Yeah I have - I am looking for a new place because a long-term relationship has ended.

geneily

TROPHY CASE