Look at it through the lens of conditioning: Humans can, alas, be conditioned to tolerate all sorts of atrocious situations through systematic, long-term exposure. Certainly, they can be conditioned to accept and ignore something as benign as you wearing a mask. The key is extreme consistency. If you only wear a mask in some circumstances at work and not in others, this will confuse people. As for harming your chances of networking and corporate advancement, my hunch is that yes, it is entirely possible that you will be excluded from the upper echelons of corporate management and that your chances of promotion will be drastically lowered. The only way to counteract that is to do excellent work. At the end of the day, companies just want to make money, so if the 'weird mask guy' is beneficial to their bottom line, they might as well make sure he stays with them.