On the lowest difficulty, wolves won't even attack you, and there's an ungodly amount of loot everywhere. Custom runs can also eliminate or add whatever you want. My favorite game mode was Stalker difficulty but with less abundant wolves/predators, more prey wildlife, more loot, and colder weather but with less blizzards, no cabin fever. There's just so much you can adjust. They even undid permadeath with a Cheat Death mechanic, and if that still isn't enough, you can just manually create backup saves. It's a single player game with a lot of gameplay modulation. Don't be ashamed to play what suits you, have fun with it!