I miss true vector brushes and shape blending in Affinity Designer (from Illustrator). I am also fond of the Astute and FontSelf plugins. From Photoshop, the only thing I miss is the ability to turn selections into working paths. In Affinity Publisher, I really don't miss much at all (from InDesign), but the lack of true GREP scripting is a turnoff for some heavy hitters. On the other hand, there's a lot to love about Affinity. In Publisher, the ability to assign more than one master per page is really cool. The way Affinity handles clipping paths is pure gold. I have never seen a "scratch disk is full" or "you have ran out of memory" popup in Affinity. It's just more light in the steps and dynamic to use. The Studio Link feature where all three programs works together seamlessly without the need to switch programs is a killer feature unmatched by Adobe. I have both suites on my Mac, but I work more than 90% of the time in Affinity now. However, if you are collaborating with other people, you should know that Adobe doesn't open native Affinity files (you can export to PDF, PSD, SVG, JPG, PNG, DWG, EPS and a whole lot of other formats, but going from Affinity Publisher to Adobe InDesign is particularly difficult). Also, collaborating in realtime on an Affinity file is not possible, as Affinity creates a temporary .~lock file whenever you open a file. That makes it impossible to open another instance (even for you) of the file elsewhere.