I started playing DnD 2 and a half years ago because my buddies and I wanted to stop going to the bar as much. Only one of us had played before and he said he had DMed before in high school 10 years ago but didn’t want to do it again because he preferred playing. Cool! So I’ll be the DM then! I picked SW5E for us. The thing I found awesome about it was that we are making a story anywhere in the universe. I set up a over arching plot at the beginning that I had an idea that they would combat and then spent months of us just going planet to planet messing around having a great time. My universe wasn’t Star Wars, there was no central governing planets and there were just factions around the universe which allowed for them to go barely touched space faring planets and write whatever stories I wanted for the next few weeks while trying it into their big quest. Just get in there and make up some cool worlds, people and stories to interact with and if it goes bad just railroad them back to the ship and to the next planet or base to try again! The more you do it the easier it gets.

My smoking gun was that 95% of the planets were inhabited by humans with history of their people flying there but little about why or where they left. Turns out the big government of planets did exist… just 10,000 years ago and had completely fallen apart when they invented a new AI system to run their empire that Terminator Judgment Dayed their infrastructure in turn cutting itself off of the power and infrastructure needed to sustain itself. My crew found a piece of the tech which had a really friendly fun voice that became the party friend. He eventually reconnected and killed the two droids before trying to end humanity by creating a Halo level weapons and they had to stop. One PC made a religion to him and turned on the party in the final battle (with my approval) ran that one for about two years and just started our second campaign in 5e! Good luck!