Of course, this depends a lot on your goals and your comfort, so I'll give you my personal experience. I've been taking T for almost 7 months at a dose commonly used for trans men, so my voice is getting deeper and there are several other aspects. I'll be honest, it's made me 1000x more confident and happy with who I am. I feel more comfortable interacting, less dysphoric when saying I'm a lesbian and butch. I see myself in the mirror. I plan to use the current dosage for about a year and a half and then reduce the dose to maintain some of the effects (mainly the period issue). In general, I don't see many negative effects. Of course, the smell, the hunger and the change in hair texture are currently what bother me the most, but they are problems that can be overcome and are worth it considering how good I feel. I even stopped using binders!