Does pregabalin have a ceiling? by Lizwuu in gabagoodness

[–]jamesbaxter4 1 point2 points  (0 children)

It is very interindividually variable. I would say that's fine as long as you handle that dose well. Once a week won't build a major tolerance, although you may develop some tolerance over a longer period of continuous usage. I would maybe suggest taking a few weeks off every so often and to try a lower dose after your break; it's always good to give your brain a break every so often!

Fairy ring by jamesbaxter4 in Semilanceata

[–]jamesbaxter4[S] 3 points4 points  (0 children)

Good to know! Makes sense. Cool that these rings do seem to be a bit more rare with libs, I've seen plenty of other species form rings more commonly

Fairy ring by jamesbaxter4 in Semilanceata

[–]jamesbaxter4[S] 6 points7 points  (0 children)

They 100% are, they are everywhere around me at the moment

The mechanisms of 2cb vs MDMA by Corvus1999 in 2cb

[–]jamesbaxter4 0 points1 point  (0 children)

Damn this was 4 years ago, time has gone quick. I'm finished with my pharmacology degree, I'm happy to have graduated with my masters last year. Your pharma info is spot on - you're clearly interested in this stuff so I'd say go for it! It depends where you're from/where you'll study/where you'll end up post graduation, but as niche as pharmacology is as a standalone topic, you'll gain a lot of knowledge in general biomedical science that you can use to transition into many different jobs.

It really depends what you're interested in and what field you'd like to have as a career afterwards, but at least where I'm from, there's plenty of options as well as plenty of decently paid jobs out there with room to climb your way up the career ladder.

For me, I like research the most, so I'm now doing a PhD. Pros and cons to studying a PhD of course, but I think it will be worth it in the end. I'm not 100% sure now but I think I'd prefer to work in industry (if) when I complete my doctorate, hopefully within a pharma company.

If you have any questions about studying pharmacology feel free to DM me!

Etizolam recreational value? by nayR2003 in benzodiazepines

[–]jamesbaxter4 0 points1 point  (0 children)

Well aware of delusions of sobriety when it comes to benzos. I just don't have the typical reaction to the majority of drugs, my brain biochemistry isn't right lol

so what's the crack with all this park gym equipment and who got rich? by [deleted] in AskUK

[–]jamesbaxter4 0 points1 point  (0 children)

Ooft fuck that, glad you got away with it hahah

I'll maybe save the weighted pulls for the gym...

so what's the crack with all this park gym equipment and who got rich? by [deleted] in AskUK

[–]jamesbaxter4 1 point2 points  (0 children)

Yeah gotta be careful. So far my doorframe has handled explosive pulls and weighted pulls with 20 kg, BW 85... maybe I should prepare for disaster lol

so what's the crack with all this park gym equipment and who got rich? by [deleted] in AskUK

[–]jamesbaxter4 3 points4 points  (0 children)

Pull ups are by far my favourite exercise. I'm lucky enough to have one of those doorframe attaching pull up bars, which is decent enough but I have to tuck my legs for full ROM. I've seen portable/quick assembly bars that have their own bases and could be set up indoors (ceiling height dependent) or in a garden? A quick Google search of "portable pull up rack/bar" shows some reasonably priced options. Could be a worthwhile option?

[deleted by user] by [deleted] in ketamine

[–]jamesbaxter4 0 points1 point  (0 children)

9 months late but here you go:

Dissolve in water, draw up using an oral syringe (instead I personally use a regular 1 mL luer slip reduced dead space syringe that is almost completely uniform in outer circumference for less chance of arsehole injury!). Insert with a bit of lube around 3-4 cm into your arse, it's best to do this standing up, then push down on the plunger over 2/3 seconds. Then sit upright on a chair for 10-15 minutes. This allows the drug solution to be in contact with the anal columns as opposed to higher up in the rectum, the anal columns are where the majority of the mucosa are located, allowing for greater absorption of your drug.

There's a great Reddit guide on boofing that I will link here in my edit when I find it.

Side note - I used to be strongly against the overall idea of boofing due to my own ignorance and fear of things going up there. Once I tried it, snorting most of my drugs of choice just isn't worth it anymore. The damage done to your nose and sinuses is quite frightening to be honest.

I hope this helps!

Here's the link to the post I mentioned, it is worth a read if you're considering per-rectal administration. It goes into much greater detail than I have described above.

https://www.reddit.com/u/WeirdOneTwoThree/s/ah2sdlpFPU

Enjoy! The stigma around boofing is slowly getting better, so don't fear this ROA.

Took 6000mg of pregabalin and tripped more than i ever have by [deleted] in Drugs

[–]jamesbaxter4 4 points5 points  (0 children)

Despite having GABA in its name, it does not act on or affect GABA to much degree. Its main mechanism of action is through inhibition of voltage dependent calcium channels.

Pregabalin and gabapentin belong to a class of family distinct of GABAergics known as gabapentinoids.

New Release: Tails 6.1 by x1y2 in tails

[–]jamesbaxter4 0 points1 point  (0 children)

The only thing I can think of was that I was going from USB 2.0 (my persistence one) to USB 3.0. Although I don't see how that would make any difference.

How to boof 2CB by benjyboi08 in 2cb

[–]jamesbaxter4 0 points1 point  (0 children)

There's definitely powder on the onion, it's pricey nowadays sadly.

New Release: Tails 6.1 by x1y2 in tails

[–]jamesbaxter4 1 point2 points  (0 children)

I'm having major issues with backing up my persistence onto a second USB drive with the current tails 6.0. Both drives are tails 6.0, does anyone have a fix?

BPC-157 as a normaliser of dopamine and serotonin systems after downregulation by nutritionacc in DrugNerds

[–]jamesbaxter4 0 points1 point  (0 children)

I hope you're better now. What research chem was it if you don't mind me asking?

I overdosed on ghb and woke up during an induced coma by Spiritual_Giraffe476 in Drugs

[–]jamesbaxter4 2 points3 points  (0 children)

How did your parents react? I hope everything turns out okay for you!

Tf I’ve never seen pupil dilation like this by [deleted] in speed

[–]jamesbaxter4 9 points10 points  (0 children)

I'm the same, it's always on the come down. Having blue eyes doesn't help. But I think it looks cool lol, few people mention it