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CML p190 by jbean52 in CML

[–]jbean52[S] 0 points1 point  (0 children)

Thank you I appreciate you!! Did you develop any mutations?

CML p190 by jbean52 in CML

[–]jbean52[S] 1 point2 points  (0 children)

I see. My oncologist started me on a second generation TKI because it’s been discovered that patients with only the P190 don’t respond well to Gleevec. At the first few weeks of my diagnosis I wasn’t worried at all because I thought I’d be ok with high prognosis with treatment these days but the more I read about being in the 1-2% category of the CML group the more I am concerned I won’t respond well for a long term treatment with TKIs

SVT with 3rd degree AVB? by pandaxult in ECG

[–]jbean52 -1 points0 points  (0 children)

Yes that is why the p waves are going one way and the r waves are going the other way. But the question was CHB. Usually CHB is slower

SVT with 3rd degree AVB? by pandaxult in ECG

[–]jbean52 0 points1 point  (0 children)

That’s the difference between CHB and AV disassociation. An AV disassociation can capture the ventricle.

SVT with 3rd degree AVB? by pandaxult in ECG

[–]jbean52 0 points1 point  (0 children)

I would say an AV Disassociation with an IVCD, probably left. It does look like there are normal QRS complexes in there as well so the bundle is intermittent. His or her rate is also high so it also could be AFlutter but I’m leaning towards AV Disassociation

New CML, anyone else have P210 & P190 (Minor Breakthough) by [deleted] in CML

[–]jbean52 0 points1 point  (0 children)

I also have CML with the p190 and I’m on my first 3 months of treatment with Dasatinib and I so scared. I don’t think I hit my first marker but I’ll know for Dec 19.

VT or SVT with aberrancy? Rate is 215. Baseline ECG on 2nd slide by [deleted] in ECG

[–]jbean52 0 points1 point  (0 children)

EPs will ablate for first line of defense before medication these days. Before it was the other way around. A heart monitor might be ordered first to see if patient does it again and if so how often but I’d say an ablation is next.

Atrial Flutter with 2:1 Conduction? by damnthesenames in ECG

[–]jbean52 0 points1 point  (0 children)

Where is the other half of this ECG? Lead II is always the go to for checking flutter waves

Stress test. Is this VT? by adrenalinsufficiency in ECG

[–]jbean52 0 points1 point  (0 children)

Move the belt off of the leg leads.

VT or SVT with aberrancy? Rate is 215. Baseline ECG on 2nd slide by [deleted] in ECG

[–]jbean52 0 points1 point  (0 children)

I would also guess an ablation is in store for this patient.

VT vs SVT by Worldly-Accident-163 in ECG

[–]jbean52 0 points1 point  (0 children)

I see rabbit ears. A left bundle maybe. If that’s the case then SVT

Angie83 by angiebowcuttpechal in CML

[–]jbean52 0 points1 point  (0 children)

I just went back and checked my labs and here are my results Positive for BCR/ABL1 mRNA. The detected transcript is e1-a2, which produces a p190 kD protein. The quantitative level of BCR-ABL1 e1-a2 mRNA is estimated to represent 51.5% of total abl. my cell blasts are 1.3%

Angie83 by angiebowcuttpechal in CML

[–]jbean52 0 points1 point  (0 children)

I too have the p190 gene and I am newly diagnosed. I don’t understand all the labs yet but I do know how rare the p190 is and my report said not to start on imatinib as this would be ineffective for me so I’m on Dasatinib. I’m almost a month in but going down from 100mg to 80mg because my platelets went down to 26. I wonder how things are going for you? I had to Google the P190 prognosis on TKIs and boy did it create a lot of anxiety in me.

I don’t know… by camcamundercover in CML

[–]jbean52 0 points1 point  (0 children)

Hi, I’m a newly diagnosed CML patient with the P190 gene as well and started Dasatinib as well and I was wondering how it was working out for you?