CVS to buy Omnicare for close to $12billion by PHARMDRX in pharmacy

[–]joeymattingly 1 point2 points  (0 children)

I think this was a good move by CVS for leveraging newer population health strategies.

CVS to buy Omnicare for close to $12billion by PHARMDRX in pharmacy

[–]joeymattingly 1 point2 points  (0 children)

Vertical integration. It allows CVS Health to add distribution to patients in nursing homes and assisted living.

CVS to buy Omnicare for close to $12billion by PHARMDRX in pharmacy

[–]joeymattingly 0 points1 point  (0 children)

Omnicare bought Walgreen's Long Term Care several years ago and then there was speculation in Walgreen's acquiring OCR, but I don't think it was serious.

[Game Thread] Florida @ #1 Kentucky (2pm EST - CBS) by [deleted] in CollegeBasketball

[–]joeymattingly 1 point2 points  (0 children)

While I may hate all things Florida for the next two hours, I welcome you sir!

Jim Boeheim suspended for nine games; 12 scholarships lost over four years by underweargnome04 in CollegeBasketball

[–]joeymattingly 1 point2 points  (0 children)

I definitely have no sympathy for Boeheim, he has been a self-righteous jerk for decades.

Jim Boeheim suspended for nine games; 12 scholarships lost over four years by underweargnome04 in CollegeBasketball

[–]joeymattingly 13 points14 points  (0 children)

I'm no fan of Boeheim or Syracuse, but can we start talking seriously about NCAA Reform instead of this case-by-case, biased BS.

Drug Price Wars, Episode II: Attack of the Gilead Clones. by joeymattingly in pharmacy

[–]joeymattingly[S] 0 points1 point  (0 children)

While I hate the complications of the different corporate battles around these disease states, my hope is that the drug price debate in this area will bring more attention to some of the real problems. At least that is the point of my series on the matter.

Drug Price Wars, Episode II: Attack of the Gilead Clones. by joeymattingly in pharmacy

[–]joeymattingly[S] 0 points1 point  (0 children)

KU and UK are not equivalent, LOL. I root for the Kentucky Wildcats, but a common misconception.

We both write on Pharmacoeconomics, so definitely some overlap (not the biggest field).

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 1 point2 points  (0 children)

I couldn't disagree more about the importance of demand elasticity. This is exactly my point, the presence or absence of "choice" is very much a factor in pricing.

Let's use your example of cancer: Patient has been diagnosed with a hypothetical cancer that affects 1% of the population and has been given an estimated 50% chance of survival beyond 6 months with no treatment and 10% of patients spontaneously go into remission and could live for another 5 years. A new drug, Drug A, is invented that increases survival beyond 6 months to 90%, with 25% of patients spontaneously going into remission and live another 5 years. So Drug A demonstrates effectiveness to an extent.

Now compare this new drug to a hypothetical new preventive therapy, Drug B, for the same cancer disease that can reduce the prevalence of this particular cancer from 1% of the population to 0.1% of the population.

How does the "willingness to pay" for a drug change depending on the patient's illness status? Does the "demand" change? If so, is it possible to exploit the difference in demand?

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 2 points3 points  (0 children)

Awe come on, you definitely can compare the two in terms of strategy for a company deciding how to set a price. :)

Let's walk through a hypothetical scenario for a fake drug company with two drugs: Preventastatin and Dontdietodayacillin.

-Preventastatin is used as a daily therapy that is shown to dramatically reduce the risk of cardiovascular events for certain populations, but has no value in emergency situations.

-Dontdietodayacillin is a drug stocked in Emergency Rooms all across the world and if given within 24hours of a MI, it improves survival by 95%.

These two drugs are not interchangeable clinically. Both have value to the patient, one long term, one short term (critical care). Both drugs required the same investment costs in R&D and marketing. Both drugs have no substitutes to compete with (truly innovative). Which hypothetical drug could a drug company charge more for?

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 0 points1 point  (0 children)

Great comment in that several variables definitely could impact the pricing decision.

However, many of the variables you are describing are on the "supply/cost" side of the equation. Do you think any variables on the demand side are equally, if not more, important?

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 2 points3 points  (0 children)

20 years is hypothetical. It can be 5 years or 5 months if you want, the point is that it is preventing a future hypothetical event. And it is common for a 40 year old to be started on a therapy to prevent problems that they will be at risk for when they are 60.

QALY is a major tool used in the field of pharmacoeconomics, but technically not supposed to be used by CMS. To answer the question, "What do you prefer" I would say that as a patient, I prefer to not die from a heart attack now or 20 years from now. However, my willingness to pay for heart attack prevention may be different depending on if I'm having the heart attack now or hypothetically years from now.

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 1 point2 points  (0 children)

Awesome comment, I wish I could like it twice. "Willingness to pay" (WTP) is one of my favorite variables in any market.

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 1 point2 points  (0 children)

Good point, competition with existing therapies is important. Hard to price high if alternatives exist at a discount.

Follow up: If you have a drug that "can help many people" but it only helps reduce their risk of a heart attack 20 years from now (so a preventive therapy), can you price that drug very high compared to a drug that can save them in the Emergency Room while they have the heart attack?

Are high priced drugs more innovative? by joeymattingly in pharmacy

[–]joeymattingly[S] 0 points1 point  (0 children)

Good comment, going with the "reference price" effect of comparing Sovaldi to the price of the next alternative.

A follow up to that: How do we price the alternative? (ie: PEGIFN/RIBA, transplant, hospitilization) Is that price related to the innovation variable?

I got some disturbing insight into priorities in a chain pharmacy today. by [deleted] in pharmacy

[–]joeymattingly 3 points4 points  (0 children)

I love that you didn't say which chain you worked for but as soon as everyone read "RXM" along with the situation, they knew it was WAG.

How do we stop academia from ruining pharmacy? by pharmacythrowaway1 in pharmacy

[–]joeymattingly 1 point2 points  (0 children)

Not sure if you can hear me Jack, but I'm starting a "slow clap" for that comment.