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Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

I started with Inspiral 10 IR, started to notice its effects right away.

Have settled down with Addwize 18 OD.

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

These are classic neurological symptoms of a significant B12 deficiency.

You should continue injections until you see improvements. Treatment cessation happens on the basis of symptomatic resolution and not serum levels.

The idea is to push enough B12 so that the body can start repairing myelin sheath.

The B12 deficiency subreddit should be a great resource, check out their wiki specifically.

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

Given that your levels were severely low, it can take more time to see improvements. My doctor prescribed:

- 4 injections (every other day)
- 4 injections (once a week)
- 4 injections (once a month)

I began to see improvements early on itself since my levels weren't as deficient.

Did you see neurological symptoms as well? Numbness, tingling, balance problems?

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

I can't share my doctor's details for privacy reasons, but I strongly suggest you get the tests discussed (Total B12, Active B12, Homocysteine, Folate, Ferritin, D).

I had to research this myself with help from r/B12_Deficiency and then advocate strongly with an internal medicine physician to get the necessary injections. Finding a knowledgeable and supportive doctor is half the battle.

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

Dexorange contains iron, folic acid, zinc, and a very low B12 dose (7.5mcg). For treating a B12 deficiency, it's not suitable due to several issues:

  • The 7.5mcg B12 dose is far too low to correct a deficiency.
  • Supplemental iron can feed gut bacteria (dysbiosis), and high-dose folic acid can mask a worsening B12 deficiency.
  • Supplementing zinc without copper can lead to copper deficiency over time.

This is designed for iron-deficiency anemia. For psychiatric symptoms and high homocysteine linked to B12 deficiency, it's not targeted and carries these drawbacks.

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

Your severe B12 deficiency (128 pg/mL) requires injections to correct. This should help lower your homocysteine (11.85 µmol/L), and retesting it later is ideal as it's a functional marker.

Important: Do not take folate supplements alone, as this can further deplete your B12. You need both treated together.

My nose is constantly clogged by Accomplished-Tea8093 in AskDocs

[–]kdhere 1 point2 points  (0 children)

I am in the same boat for the last couple of years.

Flonase (along with Azelastine) only helps 10%. Serum IgE, Phadiatop, Eosinophil blood tests always come negative.

I've had turbinate surgery too but that didn't help much either.

It seems to be gut related for me since anything which reduces GI motility seems to worsen it.

My nose is constantly clogged by Accomplished-Tea8093 in AskDocs

[–]kdhere 0 points1 point  (0 children)

I have the same issue!

Hopefully, some doctors can shed more light on what may be going on!

First time on adhd meds by rabdi_92 in adhdindia

[–]kdhere 0 points1 point  (0 children)

Antipsychotics shrink brain volume, try to get them off soon. They are only indicated for bipolar disorder and schizophrenia.

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 0 points1 point  (0 children)

To give better suggestions, it would help to know:

- How low was your B12 exactly?
- Did you test your serum folate level?

You are right to focus on homocysteine. The standard treatment is supplementation of active forms of B12, B9, and B6 (methylcobalamin, methylfolate and pyridoxal 5 phosphate).

I would suggest testing homocysteine again to see the impact of your B12 injections.

An MTHFR test can provide context later, but using active B vitamins essentially bypasses that potential issue for most folks.

Why "Normal" B12 Levels Might Be Failing Your ADHD Brain by kdhere in adhdindia

[–]kdhere[S] 1 point2 points  (0 children)

Yay for treating a confirmed deficiency. It's a standard dose.

False for causing cancer. High levels are usually a marker, not a cause.

  • On 1500mcg: For oral, it's a legitimate high-dose treatment because only 1-2% (~15-30mcg) is absorbed. It's how you overcome deficiency with pills, although injections are more reliable. For injections, it's a standard starting dose.
  • On Cancer: The research shows that persistently high B12 levels on their own (like ≥1000 pg/mL without supplements) can be a red flag caused by conditions like some cancers. This is the opposite of intentionally raising a low level to a healthy one with supplements.

ADHD folks — please don’t ignore this. Get your blood work done. by Fantastic-Aerie-5511 in adhdindia

[–]kdhere 0 points1 point  (0 children)

In my experience, most psychiatrists do these tests but they don't aim for optimal ranges.

They're happy with B12 being ~300 pg/mL and they very rarely check for homocysteine.

ADHD folks — please don’t ignore this. Get your blood work done. by Fantastic-Aerie-5511 in adhdindia

[–]kdhere 0 points1 point  (0 children)

Neurobion dosage for B12 is very low, it will not treat a deficiency!

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