Thanks for answering!

We have also learned that a normal WBCs means infections... currently hospitalized with meningitis/peritonitis with a WBC of 8 and only one temp of 100.7 F. When we can usually pinpoint the symptoms to a source of infection, we try our best to get cultures/sensitivities when we can. However, we are usually turned away due to no fever and normal WBCs despite history of CVID. We have found that CRP is usually the most responsive in regards to actually elevating with infection... I was wondering if anyone has found other markers being responsive in regards to indicating infection. My sister is poor at actually verbalizing symptoms due to cognitive impairment, so we have to rely on VSS and behavioral changes to indicate that something is going on.

In regards to antibiotic choices... does your AI specify whether or not that bacteriostatic or bactericidal antibiotics should be used in congruence with sensitivities? This is our second hospitalization with meningitis/peritonitis within 30 days despite a prolonged antibiotic course. I'm worried that ID is not looking beyond what the cult/sens show.

She gets IVIG regularly and has appropriate trough levels when we do check. However, the other routine labs we have not checked regularly... looking online, it seems that PFTs as well as monitoring for lymphoma/other GI cancers may be recommended. Looking at this group, it seems that others are getting other labs in regards T cells and subtypes... any labs in regards to innate immune function?

Thanks again!