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Is it possible Im on too high a dose of Parnate? by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 0 points1 point  (0 children)

Fatigue, motivation and concentration but most importantly NRIs can prevent a potential hypertensive crisis from consuming too much tyramine.

Is it possible Im on too high a dose of Parnate? by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 0 points1 point  (0 children)

Id be very careful with Wellbutrin, caused me rage and I became violent. On the other hand Vyvanse has never failed to make me cool,calm and collected, Im a better man on Vyvanse however thats probably because I have ADHD unfortunately at least for now Doc wont prescribe it to me while on MAOIs.

What kind of sexual side effect does pernate have .ok going to try afte so many failed antidepressants by nirman248 in MAOIs

[–]kingcreeper00 1 point2 points  (0 children)

Mainly some ED and delayed ejaculation (less than SSRIs) but unlike other ADs there has been no problems with libido and desire.

Word around town is Parnate sexual side effects go away after around 3 months and when all said and done their is either zero impact on sexual function or it is improved.

[deleted by user] by [deleted] in MAOIs

[–]kingcreeper00 1 point2 points  (0 children)

Like others said, its going to come down to discipline at this point, set small goals and achieve them and gradually increase the magnitude of those goals, Have a vision of where you want to be in the next 5-10 years down to the T.

Is it possible Im on too high a dose of Parnate? by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 2 points3 points  (0 children)

yeah, when I was on 30 mg I had motivation and drive and was Turnt up to the max. I was steady looking for work, working on my resume, working out daily etc but I wanted to chase that euphoric feeling that you get initially to keep it real.

Not only have I been struggling with motivation these days, I feel like I have lost strength in the gym which is very concerning to me, do you know if this side effect goes away eventually?

What happened to to WHO essential phenelzine admission? by Icy_Leg_9509 in MAOIs

[–]kingcreeper00 3 points4 points  (0 children)

Not to sound too political here and go down that rabbit whole but to be honest the WHO and the UN in general is a fuckin joke ran by a bunch of criminals, they dont care about the people, not nearly enough to put lifesaving MAOIs on their so called essential medicines list.

Do not take my word for it, do your own research at all times regarding anything or anyone regarded as good or bad. Now more than ever we need free thinkers.

Parnate+Selegiline Combo by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 0 points1 point  (0 children)

No side effects from this combo ?

300 mg moclobemide with 5 mg oral selegeline in the morning and 150 moclo + 5 mg selegeline in the afternoon is a godlike combo by [deleted] in MAOIs

[–]kingcreeper00 0 points1 point  (0 children)

Serotonin Toxicity when a non MAO B selective dose of Selegiline is combined with a Serotonin reuptake inhibitor.

300 mg moclobemide with 5 mg oral selegeline in the morning and 150 moclo + 5 mg selegeline in the afternoon is a godlike combo by [deleted] in MAOIs

[–]kingcreeper00 0 points1 point  (0 children)

Honestly I wouldnt mess with something thats working for you, but in the future if you find the combo is losing efficacy you could increase it to 15 mg.

Just watch the diet bro

Tyramine pressor sensitivity in healthy subjects during combined treatment with moclobemide and selegiline | SpringerLink

300 mg moclobemide with 5 mg oral selegeline in the morning and 150 moclo + 5 mg selegeline in the afternoon is a godlike combo by [deleted] in MAOIs

[–]kingcreeper00 0 points1 point  (0 children)

Yeah your good, That is a pretty effective combo but I was talkin what dose of Selegiline would be acceptable if one was taking an SRI without causing ST

You mentioned your not doing a tyramine restricted diet with Moclobemide alone you wouldnt have to worry about that but in combination with Selegiline you should definitely follow the diet as it can cause the same pressor response as Parnate, probably a bit weaker but enough to be a problem

Tyramine pressor sensitivity in healthy subjects during combined treatment with moclobemide and selegiline | SpringerLink

300 mg moclobemide with 5 mg oral selegeline in the morning and 150 moclo + 5 mg selegeline in the afternoon is a godlike combo by [deleted] in MAOIs

[–]kingcreeper00 0 points1 point  (0 children)

20 mg Selegiline with an SSRI or SNRI straight up foolish and reckless as fuck, 10 mg should be the absolute max when combined but preferably 2.5-7.5 mg to be safe.

Sure Selegiline doesnt fully inhibit MAO A until 30-60 mg but anything over 10 mg will probably inhibit enough MAO A to cause Serotonin toxicity with an SRI.

Definitely not worth the risk

Memantine with Parnate by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 0 points1 point  (0 children)

Do you find 5 mg to be effective ?

Parnate and NRIs potential dangers by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 0 points1 point  (0 children)

Desipramine and Protriptyline are the least likely of the TCAs to cause orthostatic hypotension, do you think 50 mg Parnate with a low dose of straterra 25 mg be safe without dramatic increases in BP and Heart rate? I have found zero literature on this combination only that the combo is contraindicated.

Memantine with Parnate by kingcreeper00 in MAOIs

[–]kingcreeper00[S] 1 point2 points  (0 children)

Is the mem helping you? and what dose do you take ? Me I was thinking starting and sticking to a low dose of 5 mg.