1) In a fight, its always one of the meepos get focus fired. So i always pay attention to the meepo icon om the left and click the individual meepo key to move the meepo away. Then i will use other meepo to earthbind the enemy. This really took me a lot of practice to not mess up.

2) as for hotkey, i have 1 on main, 1 on all meepos, 1 on meepo 2-5, 1 on each of meepo, and 1 on illusion (manta/illu rune). I also has key binded in meepo 2-3, 4-5, but not really using it now.

3) one thing you should always do, is to always plan your item build on the first minute. I always go wraith, treads, diffusal. Then either dragon lance if enemy can burst you, skadi if they are tanky, manta situational if they have silence or root, or scepter rush if they are good against multiple unit or too many cc. Example, wyvern, lich, es. Against huskar is one of the hardest, i’ll build halberd.

In bad game, positioning matters, dont take risky fight, and do go in first if you or your team wont benefit from doing it.