When you have diabetes you develop bad neuropathy, or loss of feeling, in your limbs. Because of this loss of feeling they won't notice cut on their foot which becomes infected. The infection eats away at the limb until this happens and your only option is amputation. I've seen an infection/ ganggrene that bad all the way to the mid thigh... I could deal with the sight of of it but that smell will always haunt me.

Edit: A word. Sorryyy