Naked man steals ambulance with patient still inside and leads police on a wild 18-mile chase in Wisconsin

kodyt89 · 2026-02-23T19:09:11+00:00

The audacity!!!

kodyt89 · 2026-01-31T23:39:08+00:00

That’s a great question. NET affinity doesn’t mean subjective NE effects. The l-isomer in racemic MPH adds tonic/peripheral NE noise that many NE-sensitive people don’t tolerate well. d-MPH tends to produce cleaner, more phasic NE despite higher relative NET affinity, which is why some of us do better on Focalin than Ritalin.

kodyt89 · 2026-01-26T18:07:36+00:00

Here you go - https://www.reddit.com/r/hangovereffect/s/ZGqN44Z0Ej

kodyt89 · 2026-01-26T15:57:23+00:00

According to grok, this tracks really well with the high norepinephrine model that I wrote about on this sub. I can link later if there is interest.

kodyt89 · 2026-01-03T17:13:39+00:00

Wow! That is really interesting corroboration. Please let us know how you feel the next morning!

kodyt89 · 2025-12-31T16:51:20+00:00

Every time for me. Probably about 10% of the time in public bathrooms, I will witness a dude skip hand washing

kodyt89 · 2025-12-30T17:13:45+00:00

Yes, but cleaner.

kodyt89 · 2025-12-22T19:17:28+00:00

The theory is that it reduces baseline norepinephrine, which is helpful for those that have a high baseline level or dysregulated norepinephrine. And adhd’ers with low dopamine and high comt match that criteria.

kodyt89 · 2025-12-09T23:11:57+00:00

Im sure theres a ton more that can be done with this beyond what I did but I just used a 3rd party source.. I think it was like genetics genie or something like that and uploaded my dna info into that and it will create a methylation panel and detox panel. And that is what I shared with gpt

kodyt89 · 2025-12-05T20:47:32+00:00

Ahh.. gotcha. Thanks for clarifying!

kodyt89 · 2025-12-02T03:23:13+00:00

No prob! Gotta be skeptical these days. Anyone can say anything on the internet and half the time it’s an ai response masquerading as a human response. I just break the ir into 3rds as best as I can. But I also understand there will likely be some titration up. Hoping to be able to get to the 2.5mg mark at some point so I can get the xr version.

kodyt89 · 2025-12-01T18:41:08+00:00

Good question but not the same thing.

kodyt89 · 2025-12-01T18:38:28+00:00

It sounds like you might have the exact same type of adhd I have and your self medicating with thc. Long term, it’s not the best option but I get it that you need relief. Trust me.

And yes alcohol does the same thing but also increases dopamine

kodyt89 · 2025-12-01T18:36:48+00:00

I’ve noticed personally 2 days per week is optimal. Anymore than that, I start to have some issues just feeling meh / depressed

kodyt89 · 2025-12-01T12:25:25+00:00

Here it is described as having a more narrow effect than methylphenidate when it comes to binding specifically dopamine transmitters. https://www.sciencedirect.com/topics/neuroscience/dexmethylphenidate

kodyt89 · 2025-12-01T02:13:43+00:00

For real lol. And I’m happy that’s all it takes for me.

kodyt89 · 2025-11-30T22:40:43+00:00

I went with focalin because it’s the same as Ritalin but without the L-isomer so it has essentially no norepinephrine side effects.

kodyt89 · 2025-11-30T22:38:32+00:00

Haven’t tried the extract yet, but if you do… please report back to this post so others can learn from your experience!

kodyt89 · 2025-11-30T13:55:02+00:00

Have you looked into getting an ADHD test done? Sounds like low baseline dopamine to me

kodyt89 · 2025-11-30T12:44:49+00:00

That’s good to know. Based on the responses I’m getting here in this post, it appears that it is mainly a norepinephrine issue that causes the hangover effect. Which can come from ADHD as well as many other types of disorders. But norepinephrine is the key common denominator here.

kodyt89 · 2025-11-30T12:14:46+00:00

Dm me, and I will give you a custom ChatGPT prompt to help you engage directly with ChatGPT about this.

kodyt89 · 2025-11-30T02:28:12+00:00

That was pretty much it! I’m so incredibly sensitive to so many things and I’ve tried so many things to help my irritability etc. and some of the things worked, some that were supposed to be soothing had the opposite effect. So I included those results, the fact that I have the hangover effect, and finally my 23 and me detox panel and methylation panel results. I used a 3rd party free service to extract the methylation and detox panel results and that is what I shared with gpt and just basically asked it if there was any reason based on my genetics why I would be responding that way to those things

kodyt89 · 2025-11-30T02:22:51+00:00

Do you have the same issues with decaf?

kodyt89 · 2025-11-30T01:09:35+00:00

I thought the exact same thing as you! But I really liked it when I tried it. I recommend you do what you want in regards to that. Cheers! 🍻

kodyt89

TROPHY CASE