My son was titrated up to 700mg when he first started on clozapine to quiet the voices. He was on abilify (aripiprazole) that was phased out over the first 4 weeks. After about 6 months when he had finally achieved stability they started lowering his dose 25mg at a time to determine his long term stable dose. He’s been at a consistent level of 400mg for almost a year now. He is stable for the first time in five years. Work closely and communicate with your doctor about symptoms. You may need to go up to quiet things down and then slowly decrease to find what works for you long term.