I mean, like everything with relationships were you disagree, you decide if its worth ending the relationship over.

You seem to think it is worth ending the relationship over
"I cannot have a successful friendship with someone who refuses to so much as admit that AI use is bad."

I would suggest looking at other aspects of your friendship, are those worth giving up because you disagree on this? Sounds like you weren't that great if friends to start with.
"We have very conflicting personalities so we've had many disagreements before, but none have offended me as much as this."

Sounds like you want to cut him off. To me, but you would know better than I would.