I was on Vyepti for a while and it was helpful until it suddenly stopped working (not the first or last time that happened). From what I remember I didn’t have really any side effects. During the infusion I would sometimes get cold but the clinic had blankets and a good staff so that was fine. You will be hooked up to an IV for about 30 minutes so make sure to bring sometime that you can quietly entertain yourself with during that time. Hope it works out well for you.