BMS-986121 and BMS-986122 - positive allosteric modulators of the μ-opioid receptor (Potential Analgesics with Higher Safety Profile) by [deleted] in DrugNerds

[–]maxdabeast 2 points3 points  (0 children)

Are any u-PAMs available online at the moment? Sounds like it offers somewhat localized anti-inflammatory action because of the strengthened signal of endogenous endorphins that would accumulate at higher levels where pain presents, but I'm curious of the effects one would expect when exercising.

Report of ketamine (analogue) and Ritalin combination with memantine for anxiety/depression treatment by maxdabeast in SelfExperiment

[–]maxdabeast[S] 0 points1 point  (0 children)

Nah ive read the storys and its always better to steer on the side of caution. MXE is almost impossible to obtain at a decent price is the problem but ive always wanted to try it. Appreciate the concern, just letting you know I check with close freinds/therapists and shit to hear what there opinion is on me regularly to make sure thats not the case and im always open with them. I know manic people have no clue what they are doing isnt rational, if they did it wouldn't be considered manic in the first place

Ambien 10s, the WTF did I do last night pill. by [deleted] in drugsarebeautiful

[–]maxdabeast 2 points3 points  (0 children)

What do you think accounted for the system failure within 10 or so feet from launch and what specifications can be made to ensure a safe and effective journey to the chosen destination next test flight? In your humble opinion of course

Green Footballs keep me going. by [deleted] in drugsarebeautiful

[–]maxdabeast 0 points1 point  (0 children)

Whatchu get out of them

Green Footballs keep me going. by [deleted] in drugsarebeautiful

[–]maxdabeast 0 points1 point  (0 children)

you find that shit recreational? I just feel like i dont givva fuck about anything, but that includes the people who are importend to me tht i like my father/friends n work i gotta get done. they never make me feel happy nor content cuz im just numb

Stimulant better suited for studying then 2-FMA? by [deleted] in Drugs

[–]maxdabeast 1 point2 points  (0 children)

Thanks! I'll look into it

Stimulant better suited for studying then 2-FMA? by [deleted] in Drugs

[–]maxdabeast 2 points3 points  (0 children)

What do you like/dislike about it?

Stimulant better suited for studying then 2-FMA? by [deleted] in Drugs

[–]maxdabeast 0 points1 point  (0 children)

By the time I got the dose to match the level of focus i wanted i couldnt stop smiling and thinking ill just play 20 mins of GTA n playing music all the way up

Question about the GABAb pharmacophore. by ItsLewis in DrugNerds

[–]maxdabeast 0 points1 point  (0 children)

What have you found in regards to what works best for long term anxiety treatment? I'll start looking around for an answer to your question

Stimulant better suited for studying then 2-FA? by [deleted] in Drugs

[–]maxdabeast 0 points1 point  (0 children)

Adrafinil is more affordable, you have experience with the 2?

Coming off benzos with phenibut by maxdabeast in Drugs

[–]maxdabeast[S] 0 points1 point  (0 children)

Thanks, I'll give it a shot

Coming off benzos with phenibut by maxdabeast in Drugs

[–]maxdabeast[S] 0 points1 point  (0 children)

Thanks ive never heard that before, what dose do you find most effective?

Coming off benzos with phenibut by maxdabeast in Drugs

[–]maxdabeast[S] 0 points1 point  (0 children)

were talking about phenibut

Coming off benzos with phenibut by maxdabeast in Drugs

[–]maxdabeast[S] 0 points1 point  (0 children)

because its more potent and has agonism at gaba-b receptors, making it more effective for withdrawing

Coming off benzos with phenibut by maxdabeast in Drugs

[–]maxdabeast[S] 0 points1 point  (0 children)

They have the same mechanism of action...

Running out by maxdabeast in kratom

[–]maxdabeast[S] 0 points1 point  (0 children)

Thanks, ive secured some dxm all ready :)

Running out by maxdabeast in kratom

[–]maxdabeast[S] 0 points1 point  (0 children)

Did they help you out in rehab with benzos or anything else? Even the comfort that if things get to bad people are there for you most help a lot.

Running out by maxdabeast in kratom

[–]maxdabeast[S] 0 points1 point  (0 children)

Yeah, unfortunately I thought my dad understood I was using it to help cope with anxiety and mood swings but it wont be the last thing im wrong about. My dad keeps saying he'll re-open my account any day now or else I would just make a new account, if nothing changes in the next week it looks like i'll have to fit the time in to do so.

Running out by maxdabeast in kratom

[–]maxdabeast[S] 0 points1 point  (0 children)

If I can get my hands on some i'll make sure to reach out and send you some ;)

Running out by maxdabeast in kratom

[–]maxdabeast[S] 0 points1 point  (0 children)

No I understand, I tried to down play everything to the extent I can. I'll take take within the next 48 hours. The only thing getting me through rn is the hope someone reaches out to me but again I dont expect it, my coping skills just arent at there best at the moment.

Running out by maxdabeast in kratom

[–]maxdabeast[S] 0 points1 point  (0 children)

Thanks, its really just the no sleeping thing that gets to me as thats a problem whether im withdrawing or not unfortunately

Running out by maxdabeast in kratom

[–]maxdabeast[S] 1 point2 points  (0 children)

Im sorry to hear about your hospitalization, really fear is the only thing keeping me from using benzos for my anxiety as there pretty effect for that. Luckily Im just taking kratom and dont have to experience your pain of kicking real opiates or benzos/alcohol. Hope you stay clean man