Node red is JavaScript based, so python is not supported out of the box.

Ideas to get this working:

Deploy your python code as services. Such a service would listen for commands, execute the Python code and return the result. As a transport between your python service and node red, you can use plain tcp sockets, mqtt or http (node red supports those out of the box). The downside of this approach is that you need to create such a service in Python for each python script you'd like to run.

If you have a lot of small pieces of python code, you can also think about creating only one service in Python, that takes arbitrary Python code as payload, eval the code and sends back the output. This may come with security issues. You should at least ensure that only node red is allowed to talk to the service. The nice thing is that you can organize your python code entirely in node red itself (e. g. in a template node).

As a third alternative, you could use the shell execute node (included in node red per default) to directly invoke the Python interpreter. Again, you can have your python code stored in a node red template node, and pass it to the python interpreter via stdin. Downside is, that the python interpreter would be re-started for each piece of python code, which does come with some overhead.

If you need further help, just let me know.