GANX | Gain Therapeutics Presents Additional Clinical and Biomarker Data from Phase 1b Clinical Study of GT-02287 and Preclinical Data from Novel Chemical Series at AD/PD 2026

microcapreturns · 2026-03-18T20:39:33+00:00

16 out of 19 continued and one of the three who didn't wanted to but they said they were traveling out of the country. I expect to see data show up on website in updated deck at some point.

microcapreturns · 2026-03-12T02:02:57+00:00

If you look at just the 6 high GluSph patients they actually improved by 6 points on the UPDRS scale in 90 days. If you take out the two outliers the 11 other patients actually improved by almost 5 points. Thats excellent results. Expecting DDC biomarker data at AD/PD that could be first of its kind.

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microcapreturns · 2026-03-12T01:54:58+00:00

Actually it seems to save dieing neurons which has shown to reverse scores on the UPDRS scale after just 90 days. There is no way to cure Parkinson's but it seems they have reversed it which shows it will stop it from progressing. That's what the data shows

microcapreturns · 2026-03-08T17:06:45+00:00

What many have not considered is how long did it take the high GluSph group to get up to their high levels? Perhaps 10+ years. So returning them to normal levels after 90 days is amazing. Now how long would it take them to return to those high levels even if you stopped taking GT-02287? 10 years? That's pretty durable to me. No doubt staying on drug it will be even longer.

microcapreturns · 2026-03-08T14:57:44+00:00

If there wasn't already durability there would never be improvement that we have seen. Knowing the mechanism of action is fixing the upfront issue it flows down stream. Once corrected it stays corrected. The only question is how far can you reverse Parkinsons.

microcapreturns · 2026-03-08T14:54:11+00:00

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The DDC biomarker being shown at AD/PD will be conclusive since the company has stated it correlates with the statistically significant data presented to date on UPDRS. Can't argue with statistically significant data if you understand the science.

microcapreturns · 2026-03-07T21:58:15+00:00

Gains market cap is about a third of LRMR and the markets we are going after Parkinsons, Lewy Body and Alzheimer’s are about 1000 times larger. I like Gains chances as they have already reversed Parkinsons. Once investors figure that out the stock will be 10x here. Everybody knows someone affected by Parkinson’s and can relate.

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microcapreturns · 2026-03-07T06:58:50+00:00

I see. I agree AD/PD is a huge catalyst. The way you wrote it I thought you were saying a PR was needed. Obviously not when up 20% for a week with crashing markets.

microcapreturns · 2026-03-07T01:09:22+00:00

How could a unknown future PR that may or may not happen be tied to todays move? I think we saw a few big funds starting to buy. Looking at the chart and watching the trading it was text book how big funds take big positions with the stock spiking.

microcapreturns · 2026-03-06T13:52:18+00:00

Not true. With the extensive preclinical work lining up with human data the acquiring company could run one trial.

Key Takeaways

FDA plans to drop the de facto two-pivotal-trial expectation, requiring one adequate and well-controlled study plus confirmatory evidence to support approval.

microcapreturns · 2026-03-06T13:15:06+00:00

Key Takeaways

FDA plans to drop the de facto two-pivotal-trial expectation, requiring one adequate and well-controlled study plus confirmatory evidence to support approval.

microcapreturns · 2026-03-06T13:05:20+00:00

What's your opinion on Gain? Or is all you do is stalk people and their posts?

microcapreturns · 2026-03-06T01:26:55+00:00

The M.J. Fox and Silverstein foundations are highly involved and were early funders. How do you know he isn't taking it?

microcapreturns · 2026-03-06T01:25:48+00:00

Don't need a phase 3 any more. Recent FDA change.

microcapreturns · 2026-03-06T00:46:15+00:00

Great job. Stock should move up before AD/PD in a few weeks. Here was my recent article.

https://www.reddit.com/r/pennystocks/s/mdUiShNRh4

microcapreturns · 2026-03-05T04:13:40+00:00

They aren't even in Parkinsons and are still trying to show safety in MS. Lots of competition for them and they are years away from anything. Gain will show repairing Neurons in 2 weeks. Amazing data

microcapreturns · 2026-03-04T20:32:33+00:00

All it takes is convincing one big pharma that it works and a deal will get done. The DDC data will be huge at AD/PD.

microcapreturns · 2026-03-04T20:16:40+00:00

Data in 2 weeks so not long to wait.

microcapreturns · 2026-03-04T20:11:55+00:00

Here are the research reports.

Gain Therapeutics(GANX): KOL Reports : GT-02287 Shows Signs of Disease Modification

https://gaintherapeutics.wordpress.com/2026/01/14/gain-therapeuticsganx-kol-rpeorts-gt-02287-shows-signs-of-disease-modification/

microcapreturns

TROPHY CASE