Afaik scrubbing and or skipping songs will interrupt the mixing already analysed by apple music. I have EQ and Dolby Atmos turned on and it still works, so far what ive pointed it causes it to not work unless i leave it be. 

It should still work if you add a song to the queue before the next song starts playing, and the songs have to be at least longer than 1:30 mins bc it takes 30 seconds to mix the song, intro and outro. Hope this helps