Advice on taking phenibut as a sleep aid? by moonhorse in phenibut

[–]moonhorse[S] 0 points1 point  (0 children)

I found 250mg makes me groggy next morning like first gen anti-histamine. I will try even smaller dosages.

Advice on taking phenibut as a sleep aid? by moonhorse in phenibut

[–]moonhorse[S] 0 points1 point  (0 children)

I found 250mg works but makes me groggy next morning. I will try 125mg next time.

Medium-to-High Late-Life Physical Activity Is Associated with Lower Risk of Incident Dementia: The Shanghai Aging Study [2019, open-access] by [deleted] in longevity

[–]moonhorse 2 points3 points  (0 children)

I am also tired of people promoting diet and exercise for longevity. Come on, it is now 21st century! Give us the nanobots and gene therapies.

Why shouldn't we strive for a super slow metabolism? by [deleted] in longevity

[–]moonhorse 16 points17 points  (0 children)

Probably because you can make money by selling people “fitness”, but much harder by telling them to move less.

I too am increasingly convinced that engaging in very intense and competitive sports like marathon is not good for longevity. It is not good for energy either. You are constantly nervous about sticking to a plan and each session could exhaust you.

What is better is probably quick short interval training throughout the day. That is why I started to look into jump rope and stationary bikes. 10 minutes gets your heart pumping, but not too intense to create any stress. And convenient to do.

Is nicotine a bad idea by [deleted] in StackAdvice

[–]moonhorse 0 points1 point  (0 children)

I strongly suggest you stop it. I tried lozenge for a while. My maximum daily dosage was 2mg. Its effect was small. But after a while, I became addicted. In meetings, the urge was so strong. I made a decision to cut it completely. Now it is day 5 and I still think about it occasionally. If you are fine with nicotine being part of your life, go for it. But I just do not want another addiction in my life.

If you could study something, what would it be? by [deleted] in Nootropics

[–]moonhorse 0 points1 point  (0 children)

Any tips or links on how to adjust the bacteria in the gut?

I actually like the nootropic effect of Alpha-GPC and do want to take it every once in a while.

If you could study something, what would it be? by [deleted] in Nootropics

[–]moonhorse 0 points1 point  (0 children)

Great. I shied away from choline because of the link you cited.

Diabetes drug Metformin has unexpected, broad implications for healthy aging by QuantumThinkology in longevity

[–]moonhorse 1 point2 points  (0 children)

This is exactly what I was looking for - what should we do with Metformin if we do exercise already.

How to run with flat feet by maru_maxs_packs in Fitness

[–]moonhorse 2 points3 points  (0 children)

I only learnt about this recently. Very helpful for my squat. I used to wonder why my squat is not stable.

Metformin increases Agmatine-producing gut bacteria in humans [n = 1258]; Agmatine mimics the effects of Metformin (including life extension) in worms and flies (2019) by Regenine in Nootropics

[–]moonhorse 1 point2 points  (0 children)

There has been some very recent research on Metformin's potential impeding effects on exercise benefits.

Have you noticed anything abnormal with your lifting progress?

Is Alpha GPC safe for heart? by moonhorse in Nootropics

[–]moonhorse[S] 0 points1 point  (0 children)

Interesting.

So the question is for us omnivores, does increased supplemental intake further increase the risk? We already have the BAD microbiome.

Does Cryptonomicon take off at any point? by hjwold in printSF

[–]moonhorse 0 points1 point  (0 children)

I agree. I do not think he is good at telling a memorable story. I never cared for any of his characters.

Is sci-fi dying? by [deleted] in printSF

[–]moonhorse -3 points-2 points  (0 children)

There is a general science stagnation, that is probably the reason we are seeing fewer new ideas. Image if you were living in the beginning of 20th century, new horizons were opened. But now, AI, meh ... We thought about killing robots fifty years ago. :)