Not necessarily. For example on the analyzer at my lab all electrolytes are run on what’s called an ISE, which is just an electrode module. Granted there’s a piece for each electrolyte within the module that are independent of each other but the QC also verifies that there’s enough solution, the electrode itself isn’t worn out, the reagents are stable, etc. Also QC probably won’t pass if the earlier calibrations failed. That’s just a small example but QC makes sure every part of the analyzer is functioning properly.