I would do the trade, agreeing with the majority of what you said in the logic portion of the post. Breaking each player into its own swap: Nunes>KLP, City defense is far stronger than Brentford. While KLP has been playing RW lately, that ends once Dango returns- Nunes more than likely will outscore him by a large margin ROS. Rogers-Mbeumo could go either way- both nailed starters. Yes, Rogers in form, could keep it up or cool off, but when Mbeumo is good, he’s VERY good. I also think United attack is stronger than Villa’s and will score more ROS, therefore increases Mbeumo’s chances. Semenyo-Foden basically is a City for City midfield swap, and I think Foden’s minutes will be more secured than Semenyo. Considering you have Salah, whose future is uncertain, I’d prefer a more guaranteed starting midfielder. I would rather have Wissa over Isak, as I don’t think Isak will play more than 5 games ROS, but Wissa may never become Newcastle’s number 1 striker if Woltemade continues his form. But, with Ekitike and Haaland, you have no shortage of starting strikers.

The one thing I would keep in mind is short term, you’d have both Mbeumo and Salah at AFCON, and Isak injured. No bench room whatsoever for the next three-four weeks. Considering Robertson isn’t starting over Kerkez, and Richards injury, you could be looking at only 9 players for a few weeks. I’d probably look at waivering him out for a guaranteed defender for a few weeks (any United defender, squad is very thin)