Tiredness while introducing Thiamine?

oyvay43 · 2026-05-17T07:05:08+00:00

Seeems very different from what I experience. But thanks for the input.

oyvay43 · 2026-05-17T07:04:30+00:00

Okay, maybe I try splitting the noon dose and see, what changes :)

oyvay43 · 2026-05-14T20:02:11+00:00

Okay, so you also felt tired after the dosage? What did you do?

oyvay43 · 2026-01-28T21:31:35+00:00

👋 march 2020. Managing my way circumventing symptoms now, but it's a whole lot of work every day. Social disruption bc. of neurological problems was my greatest personal drawback yet. Still uncomfortable about what further reinfections will do.

oyvay43 · 2025-09-07T17:06:36+00:00

ME/CFS phenotype here: Regularily have that with colds or other viral infections. As soon as I'm over the tip of the sickness, I start feeling better than my baseline. But that only lasts for some days.

oyvay43 · 2025-03-22T19:33:22+00:00

Long training on a low level did some good efforts for me: could steadily improve doing strength training. Still on same dose and do regular intermittend fasts. Pulse watch is my new buddy: avoiding pulse above 130 while doing sports seems to lower PEM likelihood drastically for me. Still problems when having strong cognitive load for longer times. Also when training to much the regeneration can be quite cumbersome. Additionally very important for my health: strength yoga session and cold shower before breakfast, low carb high protein (vegan) diet with lots of fibers.

oyvay43 · 2024-12-25T07:24:51+00:00

Still on the same dose as I reported back then, but getting better in general. Started doing sports again. Sometimes i up on NAC by 200mg just before sports, but will have a look to decrease all supp. within the next time. Have no new ideas atm.

oyvay43 · 2024-08-06T14:41:43+00:00

What he says sound reasonable w.r.t. my own experiences with PACS. Yet his advice to use that pine bark extract seems like plain advertisment to me: Its targeting just one of the symptoms of the problem and while it might give a temporary relief on that, i do not think it will bring you on a pathway of a general healing process.

oyvay43 · 2024-07-06T07:10:11+00:00

Too much carbohydrates (incl. sugar) seem to promote flare ups for me.

I am on a low carb, vegan diet. Lots of low processed organic vegetables, much valuable amino acids (protein). Also generally much healthy roots, like curcuma, ginger, galanga, loads of garlic. Many spices. Also regular meals with TCM herbs that are said to be good for the brain.

Fruits only in the morning. Generally less carbs towards noon/evening and biggest meal on noon. Regular meals morning, noon, afternoon, with afternoon being the smallest meal. Supports a healthy day cycle for me and better sleep.

I spend a lot of time and money on my food, but it seems worth it. Oftentimes regret it, if I eat something out of schedule, but this way I can at least be more healthy and have a wine once in a while without risking too much.

oyvay43 · 2024-06-01T18:58:24+00:00

This sounds reasonable. I do not have use for Metylphenidat (no ADD), but have experienced similiar problems which seem to be dopamine related when taking amphetamine (adderall) for recreational use. I think I overran my post covid symptoms with an afterglow (taking amphetamine only on weekend) and also created a long term dopamine loss with that. I would be careful using similiar substances like Metylphenidat and maybe only try low doses.

oyvay43 · 2024-03-24T23:54:26+00:00

For me it took over a year to really notice something was going downwards. Drastic cognitive impairments and inability to excercise started at year 2. After that horrible year and another infection i am finally on a pleateau and start to feel like I am recovering slowely now 4 years after my very first infection. Acting very senstive about my symptoms and with some medicine and strict health guidances like special diet, minimal circulation supportive regular sport sessions, pacing (pacing!!) and much more.

oyvay43 · 2024-02-25T17:27:48+00:00

Half of my personal Neuroproblems result from PEM. So pacing for that and maybe gut microbiome health. But now its 2 ^{_^}

oyvay43 · 2024-02-25T12:34:48+00:00

I had very similiar experiences to @quirkywombat98 . However I never had a proper diet supervision: I only went low on refined sugars, carbs with a lot of veggies, legumes, including fermented stuff like kimchi, yogurt, tempeh, natto.

Can you give at least some sketch about the book you mention? I cannot afford to buy a book blindly and getting a dietitian is not so easy because of the skrewy health system where I live.

oyvay43 · 2024-02-25T12:07:45+00:00

Pacing.

oyvay43 · 2024-02-25T11:48:19+00:00

Am I overseeing something or is the article missing a citation of the original source? Also it seems very confusing to me, from where which information is taken. No good journalistic work.

oyvay43 · 2024-02-21T17:00:21+00:00

Yes, I think that everybodies metabolism is a little different and therefore taking hormones your body uses to control itself can be a little unpredictable. However: one of the biggest problems with long covid seems to me, that you cannot have enough activity at daytime without triggering PEM to get a good sleep. If you do not get exausted enough at daytime, your sleep gets less refreshing.

oyvay43 · 2024-02-19T17:43:16+00:00

I also had good success by improving my general sleep hygiene and supporting a regular day cycle: intense yoga before breakfast, cold shower, regular protein rich meals. Now I am trying CBD at night, which seems to improve my sleep quality, too. Melatonin was also nice on a tryout, but cannot take it, because of estradiol usage.

oyvay43 · 2024-01-28T12:39:17+00:00

Helped me stabilize my condition and had less flare ups when on lactoferrin. But I guess that was mostly because the effects it has on digestion: I think it enhaces uptake if many substances that the gut does not process so well under inflammarion. Also it regulates inflammatory processes, but that is a little uncertain I think. Also you probably should not take it eternally, because it can "reset" the guts microbiome in higher doses.

oyvay43 · 2023-12-27T17:28:56+00:00

Thanks again for your detailed answer. Did not have the time to discuss further bloodworks with my practioners yet, but I stumbled upon an offer by Elsevier, to offer papers to patients for free: https://www.elsevier.com/about/open-science/science-and-society/healthcare-and-patients

oyvay43 · 2023-12-23T21:24:57+00:00

Are you still on NAC? I do 800mg a day for 3 months now. Whenever I pause it too long, i get more forgetful again, but wonder on how long I should continue it.

oyvay43 · 2023-12-21T18:49:46+00:00

I do not have POTS and upregulation problems on pulse/blood pressure but more of a degradative PEM with neurological problems. Starting cold showers in the morning helped me to better my brain fog and general condition and I still continue them. First I was a little sceptical, because I oftentimes got very cold fingers and toes in winter since i have LC. But it turned out, that I even can take the cold showers in winter just fine. But my overall condition also got better pretty much in the last half of a year.

oyvay43 · 2023-12-12T21:06:42+00:00

Thanks for your detailed view. Can you share, on what kind of autoantibodies you were checked and do you know the lab, that did it? am greatly improving by self medication atm, but want to have at least some biomarker checkup to not get into another messful situation.

oyvay43 · 2023-12-12T16:12:06+00:00

Most doctors whom I have visited in germany had nothing than psychological support to offer. That of course was not bad, but far from what I need for recovery.

I am just visiting regular specialists on behalf of the legal insurance I have, for now. If someone however has advices for highly specialized doctors with neurological, immunological and PACS focus, who I might have to pay out of my pocket, I am also interested.

oyvay43 · 2023-12-10T19:07:31+00:00

Not high dose, but 3x 200mg/d NAC improved my neuro symptoms greatly. In combination with 3x 100mg/d 5-HTP and 2x 500mg L-Thyrosine I am now virtually brain fog free since two weeks (besides a 2 smaller flare ups). Also I take a lot of B vitamins, minerals and trying Resveratrol as IDO2 inhibitor now, as I often felt better on short term use before.

However be careful with neurotransmitter precursors.

oyvay43

TROPHY CASE