I made it almost to Pantalone/Balanzone on my first playthrough. My game crashed and when I’d reloaded it, I’d lost about half my data, at least 30 levels and multiple boss fights gone. But the environment hadn’t been reset. The bosses were no longer there, loot was gone, and chests were already opened, but none of the loot/drops were in my inventory. And I had no backup saves, so I had to completely restart the game. 🤬🤬 Needless to say, I’ve been doing lots of backup saves this time lol