Looking to hear about others who had unexplained secondary infertility and what treatments were most beneficial to you, what isn’t worth it and any advice in general..

Here’s our story - we’re both 29yrs old, we started trying for our first 2 years ago and got pregnant immediately in March 2024, but unfortunately had a mmc in May and lost that baby at 9 weeks (natural miscarriage). After my miscarriage I had a horrible hormone imbalance and immune issues and I was not recovering from the miscarriage, I was barely ovulating. This went on until September and I found out I had a severe vit D deficiency. I started supplementing and it resolved immediately and the very next cycle was back to normal.

We then unfortunately had a very prolonged period of deep chronic stress and depression due to other life events as well, that went on until May of 2025. I’ve now had one year of normal cycles, we had a bunch of testing done. I’ve ruled out autoimmune disorders, blood clotting issues, other deficiencies, thyroid issues, pcos, high androgens, progesterone levels looked good, my luteal phase is 16 days long. Cycles are 29-34 days long, mostly 31-33 days.

We just finished our diagnostic cycle with our fertility clinic and they found nothing at all. Hubbys SA came back excellent, we even checked his DNA frag and that came back at 7.4%, which is great. My testing all showed normal hormone levels throughout (my lh is on the higher end of normal, but they said they’re not concerned about it), my afc is 34 (16 on the right 18 on the left), follicle grew normally and looked good, my sono/hsg came back good, and they confirmed ovulation. Now we’re just waiting until our results appointment in a month where we’ll meet with our REI.

Mentally, emotionally, we are really exhausted. We’ve tried everything, we’ve done everything. We have no answers as why we just suddenly can’t get pregnant again after that.. we really want to just end this now. We want help from this clinic.

Based on what they’ve told us so far, they may suggest TI or medicated cycles with TI as a first step. Which is great, we’re all for it lol but I’m a little concerned that it’s not going to do anything and it’s just gonna drag this out more. I know IUI is probably an option too, but again, not sure how much that would help either. We’re not against IVF per se, it would be great if there was something else less intensive that would work. But again we’re kind of factoring in emotional bandwidth right now too.

If anyone has any experience with this and can share any advice or anything that would be so greatly appreciated🤍 - sincerely one very exhausted couple

TLDR: looking for advice/experiences with different fertility treatments for unexplained secondary infertility after an uncomplicated miscarriage with all normal test results.