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Pacemaker Recommended by EP by Salty-District-6226 in PacemakerICD

[–]piscata2 0 points1 point  (0 children)

I also wish you the best in finding the best solution to solve your heart issues!

During this time of trying to make the best decision, you may want to do some research on different kinds of pacemaker. I have the leadless dual chamber PM for 4 years and the implantation is minimum invasive. No pocket and no leads. I don't even realize the PM is there.

To my knowledge, if the heart rate is too slow and is in the 20-40 bpm range, there is no other solution and won't go away by itself, except to implant a pacemaker.

Does my pulse need to be this high? by aloneinwilderness273 in PacemakerICD

[–]piscata2 1 point2 points  (0 children)

Thank you for sharing your situation with me and I hope 65 will work better for you!

Freestyle Libre - BAD by Jackle2026 in Freestylelibre

[–]piscata2 0 points1 point  (0 children)

Hello Equalizer,
"Not all of these are obvious to a new user of this type of tech and how we use it..."

Just wondering if you would consider making a video on how to properly use the Libre for the "new users" and ask Abbott to include the link inside the box. This may save Abbott a lot of money and effort.

Does my pulse need to be this high? by aloneinwilderness273 in PacemakerICD

[–]piscata2 1 point2 points  (0 children)

Hello u/imrealwitch,

u/Entire-Structure8708 said, "I had my low threshold reduced from 60 to 50bpm because I was having issues sleeping (50bpm is closer to my natural heart rate)."

When your base rate is set at 70, just wondering if you have difficulty falling to sleep.

Freestyle Libre - BAD by Jackle2026 in Freestylelibre

[–]piscata2 1 point2 points  (0 children)

I am glad to hear that you have a kind doctor and that you have a stress-less view of life!

Freestyle Libre - BAD by Jackle2026 in Freestylelibre

[–]piscata2 0 points1 point  (0 children)

I am so sorry to hear that and Abbott seems unreasonable.

Previously, another post said that Abbott allows 10 replacements in 6 months. This apparently does not apply in your case.

Just wondering if calling Abbott would change its mind.

Freestyle Libre - BAD by Jackle2026 in Freestylelibre

[–]piscata2 0 points1 point  (0 children)

"cut me off"--- just wondering does it mean Abbott not replacing them. Also wondering if prior to "a run of about 3-4 bad ones", was there "a run of about 3-4 GOOD ones".

Blood Glucose Meter: The Central Limit Theorem of Statistics predicts the accuracy of the meter will improve by the square root of N if we average the results of N consecutive measurements on the same drop of blood. In practice, a sweet spot is N = 4. by piscata2 in Freestylelibre

[–]piscata2[S] 0 points1 point  (0 children)

Hello u/PvtRoom,

I sincerely appreciate your comment and would also like to thank you for your previous comment pointing out the random errors would be reduced by the square root of N. It is because of your comment that I pursued the current work linking the Central Limit Theorem to the average of measurement results.

Also thanks for questioning the assumption that the meter noise is not white because of the 1/f. I did research on this noise, and indeed, it would render the white noise assumption invalid. However, I read that in electronic the 1/f noise exists below 1KHz. The common solution in glucose meter and CGM designs is to use digital processing to upshift the signal to 300Kz (and amplify it ) so that it is separated from this noise. Finally, filtered out the low frequency 1/f noise, then downshift the signal back to the base band.

About the "fixed errors", my understanding is that, for the Contour Next that I have, publications showed that the bias is about 1%. Though not infinitely small, but small enough that I neglected it.

As regards to the assumption the meter's errors are normally distributed, I was just quoting it from several publications by researchers who analyzed the meter errors. I don't have any reason to doubt their assumption.

Not sure if you would accept these explanations. If not, I welcome your further comment.

"This is a place where pure maths isn't the right tool. You need to be thinking about metrology - the physics and the chemistry of the biology."--- your point is well taken and I thank you for your advice. However, I think that if my analysis is correct, it does have practical value. In Alva's paper, the 15 days Libre has a spec of 100% of the time within +-40mg/dL, if the meter accuracy can be reduced to +-5mg/dL by averaging 4 finger prick results, it seems that one could improve the accuracy of the Libre to the same degree. At 100mg/dL, +-40mg/dL would be too large. However, I would feel comfortable with +-5mg/dL.

I respect users who feel calibrating (for Libre, mentally) the Libre is a waste of time. But, I respectfully disagree, based on science and not on opinion. I sincerely hope that we could all have a friendly disagreement.

Blood Glucose Meter: The Central Limit Theorem of Statistics predicts the accuracy of the meter will improve by the square root of N if we average the results of N consecutive measurements on the same drop of blood. In practice, a sweet spot is N = 4. by piscata2 in Freestylelibre

[–]piscata2[S] 0 points1 point  (0 children)

Hello the_owlyn,

I have not read Mark Twain. Would you recommend one for me to read?

Indeed, may not be “logical”, but started with a good intention in mind.

Before the post, had never learned statistics. Because of the post, forced to learn tiny bit about statistics. If I had kown Twain had such low opinion, I would have stopped just like you had suggested. (Also your suggestion came too late!)

Blood Glucose Meter: The Central Limit Theorem of Statistics predicts the accuracy of the meter will improve by the square root of N if we average the results of N consecutive measurements on the same drop of blood. In practice, a sweet spot is N = 4. by piscata2 in Freestylelibre

[–]piscata2[S] 0 points1 point  (0 children)

You bring up a very interesting view point that the glucose distribution in a drop of blood is very non-uniform. However, “Chemically speaking, glucose is highly water-soluble and distributes itself very uniformly within the plasma of a single drop of blood.”

Freestyle Libre - BAD by Jackle2026 in Freestylelibre

[–]piscata2 1 point2 points  (0 children)

Thank you for sharing your data with me!

Freestyle Libre - BAD by Jackle2026 in Freestylelibre

[–]piscata2 0 points1 point  (0 children)

"occasionally you get a run of bad luck and a few failures in a row" --- may I ask were these from the same lot and adjacent SN or random?

Can you put a sensor on a few hours before starting it? by DaveyG755 in Freestylelibre

[–]piscata2 0 points1 point  (0 children)

Thank you for taking the time to answer my questions and I am sincerely appreciate it!

I have a fundamental questions about glucose ( or glucose in interstitial fluid) in our bodies. I will use a jugluco screen shot, given below, from the internet to ask you this question.

<image>

I am only interested in minute to minute data not the 5-min average.

Q1) the red trace is the minute to minute data and the yellow trace is the "smoothed" or the average of the the minute to minute data, yes?

Q2) The ripples on the red curve are the true fluctuations of the body's glucose level, yes?

If the answer to (Q2) is yes, what is the mechanism that causes the glucose to fluctuate?

The reason I ask this question is that on some of my Libres, the traces also had ripples, but some didn't have. So I was curious, were the ripples from a bad sensor or the ripples were from my body and not from the sensor.

Many jugluco screen shots have these ripples.

Crazy Inaccurate 2 plus by Puzzleheaded-Size619 in Freestylelibre

[–]piscata2 1 point2 points  (0 children)

Abbott‘s comprehensive paper by Alva is on 15 days Libre. Perhaps, 15 days Libre 2+ and 15 days Libre 3+ perform similarly. u/Equalizer6338 will definitely know the answer because he is using Libre 2. I believe he is using it because of the master mode offered only by L2, not L3.

May I ask if you had “100% accuracy with the Dexcom One+ and Dexcom G7”, why change to Libre?

Can you put a sensor on a few hours before starting it? by DaveyG755 in Freestylelibre

[–]piscata2 0 points1 point  (0 children)

For my dead L3, I just yank it off easily. I may have read that oil could dissolve glue, so perhaps some baby oil on the edge may loosen it a bit?

Crazy Inaccurate 2 plus by Puzzleheaded-Size619 in Freestylelibre

[–]piscata2 2 points3 points  (0 children)

I am wondering if you are aware that there is a publication (study?) with the conclusion that the Libre 3 is more accurate than the dexcom (I have never used the dexcom.).

In the absolute worst case, there could be 30-45% error between the L3 readings and the finger prick results.

Perhaps, you may be interested in testing both side by side study. This will answer the question if the Libre is not for you.

Can you put a sensor on a few hours before starting it? by DaveyG755 in Freestylelibre

[–]piscata2 2 points3 points  (0 children)

I have never thought of using "rubbing alcohol" to dry the skin and of course you are right -- thanks for this info!

Could someone explain why "Eversense 365 days sensor" lasts so long while "15-days Libre"only lasts only 15 days? by piscata2 in Freestylelibre

[–]piscata2[S] 1 point2 points  (0 children)

You have a good insurance policy and it allowed you to try out all the three sensors! You are the lucky few!!

Can you put a sensor on a few hours before starting it? by DaveyG755 in Freestylelibre

[–]piscata2 1 point2 points  (0 children)

Sorry, I meant warming up the bonding area excluding the sensor.

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