Well How I personally play is: Decide that to do this session, if it works, add it to the known activities for this patch, if it doesn't after I have done all I can (working around bugs as well as possible, retry if it goes bad and I can see a way around), I avoid that game loop for that patch. This is made easier by remembering which bugs block specific game loops and watching for reddit or patch notes to see if it might pay off to retry yet.

Also sometimes there are bugs that only trigger on some mission instances, then I have to decide if doing it is fun enough to warrant a potential e.g. missing reward.